Non-culprit lesions (NCLs) in acute STEMI: what is the role of physiology and imaging in deciding revascularisation?

Prof Javier Escaned is Head of Section (Interventional Cardiology Section) at Hospital Clinico San Carlos / Complutense University (Madrid, Spain). He trained in the United Kingdom as Specialist in Cardiology and obtained his PhD in The Netherlands. Author of >600 indexed scientific articles on interventional cardiology, imaging and physiology (h-index 74) and over 30 years of experience as PCI operator, he regularly lectures and performs live cases at major scientific and educational meetings. He is a recipient of the European Society of Cardiology (ESC) Silver Medal and the Andreas Grüntzig Award for his contributions to the fiedl fo Interventional Cardiology. Main areas of expertise include complex PCI, intracoronary diagnostics and functional coronary angiography. His track record in coronary physiology comprises being investigator on pioneer FFR trials like DEFER (1998), collaborator with Justin Davies in the validation and clinical implementation of iFR, and developer of new tools for the assessment of coronary microcirculation. Editorial roles include Deputy Editor EHJ, Advisory Editor Eurointervention, editor of the textbooks “Coronary Stenosis: Imaging, Structure and Physiology” and “Physiological Assessment of Coronary Stenoses and the Microcirculation". Recent board positions include EAPCI board / Education Committee Chair, ESC WG Coronary Pathophysiology and Microcirculation, EuroCTO Board. Recent trials as Principal Investigator include ADVISE II, DEFINE FLAIR, SYNTAX II, PIONEER IV, Cerebral-Coronary-Connection (C3), DCR4Contrast, INOCA LongCovid and AID ANGIO. Additional interests are philosophy and music.

Dr Justin Davies is a honorary 
interventional cardiologist at Hammersmith Hospital, Imperial College NHS Trust, London. After training at Imperial College, he won a prestigious BHF research fellowship to study arterial haemodynamics. Since then he has continued to
work on the development of mathematical algorithms to aid understanding of large artery physiology and to develop new tools to assess arterial disease. The holder of several patents,
he has published widely in the field of hypertension, coronary and large artery physiology and is the winner of many national and international awards. He has several international collaborations, and is the developer of iFR and the co-principal investigator of the ADVISE studies, the DEFINE-FLAIR, ORBITA and DEFINE-PCI studies. Justin also has an interest in renal denervation, and has lead the first-in-man studies to evaluate the safety of this technique to patients with chronic systolic heart failure (REACH studies).

Dr. Pinilla-Echeverri is originally from Colombia and received her MD from Universidad de Caldas in Manizales, Caldas, Colombia. She moved to Spain to complete training in Internal Medicine and Cardiology and then moved to Canada to complete an Interventional Cardiology, non-invasive Cardiac Computed Tomography Angiography imaging and advanced Intracoronary Imaging fellowship at McMaster University, Hamilton, Canada. She also obtained a Master’s Degree in Health Research Methodology from Universidad de Cordoba; and PhD Degree from Universidad Complutense in Madrid, Spain. She actively participates in Acute Coronary Syndrome research at the Population Health Research Institute. Dr. Pinilla-Echeverri is an Associate Professor at the Department of Medicine Division of Cardiology at McMaster University and currently an Interventional Cardiology Staff at Hamilton Health Sciences and Niagara Health. She is the Program Director of the Intravascular Coronary Imaging Fellowship in McMaster University and has trained international interventional cardiologists in Imaging. She is passionate about acute coronary syndrome research and leads educational programs worldwide.

Niels van Royen is an interventional cardiologist and Head of Department of Cardiology at the Radboud University Medical Center, Nijmegen, the Netherlands. He has a background in pre-clinical research and is head of a research group on translational research in repair mechanisms in ischemic heart disease. Also he is principal investigator of several multi-center clinical trials like the TRANSIENT, COACT, REDUCE-MVI and iMODERN. These trials focus on timing of interventional procedures as well as the use of intra-coronary physiology to guide interventional procedures both in stable coronary artery disease as well as acute coronary syndromes.

A cardiologist at McMaster University, Ontario, Canada. Features in 1 video on Wondr Medical. Shamir Mehta generally speaks on Primary Percutaneous Coronary Intervention (PPCI) and ST-Elevation Myocardial Infarction (STEMI).