Ultralow Contrast PCI in complex and high risk patients - April 2024

Prof Javier Escaned is Head of Section (Interventional Cardiology Section) at Hospital Clinico San Carlos / Complutense University (Madrid, Spain). He trained in the United Kingdom as Specialist in Cardiology and obtained his PhD in The Netherlands. Author of >600 indexed scientific articles on interventional cardiology, imaging and physiology (h-index 74) and over 30 years of experience as PCI operator, he regularly lectures and performs live cases at major scientific and educational meetings. He is a recipient of the European Society of Cardiology (ESC) Silver Medal and the Andreas Grüntzig Award for his contributions to the fiedl fo Interventional Cardiology. Main areas of expertise include complex PCI, intracoronary diagnostics and functional coronary angiography. His track record in coronary physiology comprises being investigator on pioneer FFR trials like DEFER (1998), collaborator with Justin Davies in the validation and clinical implementation of iFR, and developer of new tools for the assessment of coronary microcirculation. Editorial roles include Deputy Editor EHJ, Advisory Editor Eurointervention, editor of the textbooks “Coronary Stenosis: Imaging, Structure and Physiology” and “Physiological Assessment of Coronary Stenoses and the Microcirculation". Recent board positions include EAPCI board / Education Committee Chair, ESC WG Coronary Pathophysiology and Microcirculation, EuroCTO Board. Recent trials as Principal Investigator include ADVISE II, DEFINE FLAIR, SYNTAX II, PIONEER IV, Cerebral-Coronary-Connection (C3), DCR4Contrast, INOCA LongCovid and AID ANGIO. Additional interests are philosophy and music.

Dr Justin Davies is a honorary 
interventional cardiologist at Hammersmith Hospital, Imperial College NHS Trust, London. After training at Imperial College, he won a prestigious BHF research fellowship to study arterial haemodynamics. Since then he has continued to
work on the development of mathematical algorithms to aid understanding of large artery physiology and to develop new tools to assess arterial disease. The holder of several patents,
he has published widely in the field of hypertension, coronary and large artery physiology and is the winner of many national and international awards. He has several international collaborations, and is the developer of iFR and the co-principal investigator of the ADVISE studies, the DEFINE-FLAIR, ORBITA and DEFINE-PCI studies. Justin also has an interest in renal denervation, and has lead the first-in-man studies to evaluate the safety of this technique to patients with chronic systolic heart failure (REACH studies).

Prof. Alexander Jánosi is an interventional cardiologist and currently Head of the Cath Lab and Head of the Structural Heart and Aortic Disease Program at the Department of Cardiology and Vascular Medicine at the University Hospital Essen. He graduated from medical school at the University of Düsseldorf in 2003 and was board certified in internal medicine in 2010, in intensive care medicine in 2011 and in cardiology in 2013, as well as in vascular medicine and in heart failure in 2020. His clinical interest and research include complex PCI, intravascular imaging, coronary physiology, aortic diseases (TEVAR, TAVI) and structural interventions. Prof. Jánosi is the Principal Investigator for the DEFINE-GPS trial at the University Hospital Essen.

Dr Breda Hennessey graduated from the Third Faculty of Medicine in Charles University in Prague. Following this, she returned to Ireland to complete her general medical and higher specialist cardiology training. In 2019, she was awarded the Brian McGovern Scholarship by the Irish Cardiac Society, and this allowed her to commence her subspecialty training in Interventional Cardiology at Hospital Clínico San Carlos in Madrid. She completed a two-year coronary interventional fellowship, with a focus on intracoronary imaging, invasive physiology and ultra-low dose contrast intervention. Following completion of her coronary training, she undertook a further fellowship in structural intervention, also at Hospital Clínico San Carlos. In addition to her clinical work, she has been involved in various research projects pertaining to ultra-low dose contrast PCI, investigating the impact of new technologies in reducing contrast burden in complex PCI . She has authored and co-authored a number of research articles, book chapters and has contributed to the European association of Percutaneous Cardiovascular Interventions textbook. During her time at Hospital Clinico San Carlos, she completed a Masters in Interventional Cardiology and is currently undertaking a PHD at the Complutense University of Madrid with a focus in ultra-low dose contrast PCI. Throughout her fellowship, she regularly took part in the preparation and delivery of educational courses, both at Hospital Clinico San Carlos and in collaboration with other tertiary referral centres and international cardiology societies in Spain, the UK and the UAE.

Carlo Di Mario is Professor of Cardiology at the University of Florence and Director of the Structural 
Interventional Cardiology Division of the University Hospital Careggi, Florence, Italy. Previous posts included 15 years as Professor of Clinical Cardiology at Imperial College of Sciences, Medicine & Technology, London and Consultant Cardiologist at the Royal Brompton Hospital. Despite his teaching, research and administrative commitments, he maintains an active clinical involvement performing more than 100 PCI per year with special interest in the treatment of calcified lesions, chronic total occlusions, bifurcations, and diffuse disease. He is a regular TAVI operator and certified implanter for the Medtronic Evolut R and Edwards Sapien 3 transcatheter aortic valves. He participated in more than 160 MitraClip implantations in London and Florence and has recently started direct annuloplasty with the CardioBand. Professor Di Mario pioneered the use of intracoronary Doppler, pressure measurement, intravascular ultrasound, optical coherence tomography, and near infrared spectroscopy. He was PI of the OPTICUS trial, failing to demonstrate superiority of IVUS guided stenting, and of the Lipid Rich Plaque study, due to report at TCT 2018. He was Principal Investigator of the DESTINI trial, using Doppler CRF to identify lesions in need of stenting, and of the CARESS in AMI trial, a large multicentre trial showing that patients who receive fibrinolytic therapy for ST-elevation myocardial infarction benefit from early angioplasty. This trial and a subsequent meta-analysis have led to a change in the European Society of Cardiology and AHA/ACC Guidelines for treatment of STEMI patients. He cooperated with Dr Davies to the validation of iFR to assess lesion severity and discriminate the contribution of individual lesions, and with Dr Lyon in the intracoronary delivery of SERCA-2 genes via adenoviral vectors in the CUPID2 trial.

Dr Giuseppe Colletti is a specialist in interventional cardiology at the Clinique Saint-Joseph in Arlon, Belgium where his focus is on developing and handling the complex PCI program. He did a fellowship in interventional cardiology at Hôpital Jolimont in La Louvrière, focusing on complex coronary lesions treatment with particular regards to calcified lesions, as well as at the Centre Hospitalier Universitaire de Liège – Sart Tilman. He graduated from medical from the University of Palermo on 2010 and he specialized in cardiology at the University of Sassari in 2016. Dr Colletti has been a published author in peer-reviewed journals and is planning on publishing more in the future as he has been increasingly involved in clinical research.

Prof Javier Escaned is Head of Section (Interventional Cardiology Section) at Hospital Clinico San Carlos / Complutense University (Madrid, Spain). He trained in the United Kingdom as Specialist in Cardiology and obtained his PhD in The Netherlands. Author of >600 indexed scientific articles on interventional cardiology, imaging and physiology (h-index 74) and over 30 years of experience as PCI operator, he regularly lectures and performs live cases at major scientific and educational meetings. He is a recipient of the European Society of Cardiology (ESC) Silver Medal and the Andreas Grüntzig Award for his contributions to the fiedl fo Interventional Cardiology. Main areas of expertise include complex PCI, intracoronary diagnostics and functional coronary angiography. His track record in coronary physiology comprises being investigator on pioneer FFR trials like DEFER (1998), collaborator with Justin Davies in the validation and clinical implementation of iFR, and developer of new tools for the assessment of coronary microcirculation. Editorial roles include Deputy Editor EHJ, Advisory Editor Eurointervention, editor of the textbooks “Coronary Stenosis: Imaging, Structure and Physiology” and “Physiological Assessment of Coronary Stenoses and the Microcirculation". Recent board positions include EAPCI board / Education Committee Chair, ESC WG Coronary Pathophysiology and Microcirculation, EuroCTO Board. Recent trials as Principal Investigator include ADVISE II, DEFINE FLAIR, SYNTAX II, PIONEER IV, Cerebral-Coronary-Connection (C3), DCR4Contrast, INOCA LongCovid and AID ANGIO. Additional interests are philosophy and music.

Dr Tim Schäufele is an interventional cardiologist with special interest in CTOs, coronary physiology and calcified lesions. He is owner of Kardiologie-Innenstad Bern private practice and Interventional Cardiologist at Lindenhofspital Bern. Prior to this, he served as Head of Cathlab and Interventional Cardiology at Robert-Bosch-Krankenhaus Stuttgart, after serving as a Research Fellow in Cardiac Magnetic Imaging at the Department of Cardiology University Heidelberg. Dr Schäufele is a Co-Founding Member of Transradial Workingroup German Cardiac Society, a Board Member of the Interventional Working Group of the German Cardiac Society, and a Full Member EuroCTO Club.

Angela McInerney is an Interventional Cardiologist at University Hospital Galway, Ireland. Following completion of her basic cardiology training in Ireland she was awarded the Brian McGovern Travelling Fellowship grant from the Irish Board for Cardiology Training in 2018 which allowed her to start her interventional fellowship in Hospital Clínico San Carlos, Madrid, Spain. Following two years of coronary training including complex PCI, she was awarded an European Society of Cardiology Fellowship Training Grant and completed a further year of structural intervention also in Clínico San Carlos, Madrid. Her specialist interests are in intracoronary imaging, intracoronary physiology, calcium modification techniques and complex PCI. She has been keenly involved in various research projects pertaining to intracoronary physiology and intravascular imaging having authored and co-authored a number of research articles as well as review articles and book chapters on these topics. During her fellowship she also regularly partook in the preparation and delivery of educational courses in Clínico San Carlos and values the educational aspect of her role as a Consultant Interventional Cardiologist.

Carlo Di Mario is Professor of Cardiology at the University of Florence and Director of the Structural 
Interventional Cardiology Division of the University Hospital Careggi, Florence, Italy. Previous posts included 15 years as Professor of Clinical Cardiology at Imperial College of Sciences, Medicine & Technology, London and Consultant Cardiologist at the Royal Brompton Hospital. Despite his teaching, research and administrative commitments, he maintains an active clinical involvement performing more than 100 PCI per year with special interest in the treatment of calcified lesions, chronic total occlusions, bifurcations, and diffuse disease. He is a regular TAVI operator and certified implanter for the Medtronic Evolut R and Edwards Sapien 3 transcatheter aortic valves. He participated in more than 160 MitraClip implantations in London and Florence and has recently started direct annuloplasty with the CardioBand. Professor Di Mario pioneered the use of intracoronary Doppler, pressure measurement, intravascular ultrasound, optical coherence tomography, and near infrared spectroscopy. He was PI of the OPTICUS trial, failing to demonstrate superiority of IVUS guided stenting, and of the Lipid Rich Plaque study, due to report at TCT 2018. He was Principal Investigator of the DESTINI trial, using Doppler CRF to identify lesions in need of stenting, and of the CARESS in AMI trial, a large multicentre trial showing that patients who receive fibrinolytic therapy for ST-elevation myocardial infarction benefit from early angioplasty. This trial and a subsequent meta-analysis have led to a change in the European Society of Cardiology and AHA/ACC Guidelines for treatment of STEMI patients. He cooperated with Dr Davies to the validation of iFR to assess lesion severity and discriminate the contribution of individual lesions, and with Dr Lyon in the intracoronary delivery of SERCA-2 genes via adenoviral vectors in the CUPID2 trial.

Dr Dejan Milasinovic is an interventional cardiologist at the Department of Cardiology, Clinical Center of Serbia. He is also an Assistant Professor at Faculty of Medicine, University of Belgrade. His main research interests focus in the fields of the invasive treatment of acute coronary syndromes and complex coronary interventions, with an emphasis on bifurcation PCI and intracoronary guidance. In 2016, Dr Milasinovic received the EuroPCR 2016 Best Abstract award, for a work on the timing of invasive coronary intervention in patients with non-ST-segment elevation myocardial infarction. He is a member of European Association of Percutaneous Cardiovascular Interventions (EAPCI) and has served as program committee member of the annual EuroPCR conference. Dr Milasinovic also serves on the editorial boards of EuroIntervention (editorial consultant) and PCRonline and is the Chair of the EAPCI Young committee.

Dr Enrico Cerrato is Consultant interventional Cardiologist at San Luigi Gonzaga University and Rivoli Infermi Hospital cath lab unit (Turin, Italy) the second larger cath lab in Italy for PCI (>1900 PCI/y) coordinated by Dr. Francesco Tomassini and Dr.Ferdinando Varbella. Following his training as cardiologist, he completed a formal fellowship and a PhD program at Hospital Clinico San Carlos, (Madrid -Universidad Complutense), under the supervision of Prof. Javier Escaned. Dr Cerrato is one of the founder of Cardiogroup.org, a research network that has generated multiple studies on coronary imaging and physiology techniques, particularly focusing on intravascular imaging and physiology, spontaneus coronary artery dissection and complication treatment and prevention in interventional cardiology. He recently joined the structural aortic percutaneous treatment program in co-operation with Mauriziano Hospital in Turin.

Prof Javier Escaned is Head of Section (Interventional Cardiology Section) at Hospital Clinico San Carlos / Complutense University (Madrid, Spain). He trained in the United Kingdom as Specialist in Cardiology and obtained his PhD in The Netherlands. Author of >600 indexed scientific articles on interventional cardiology, imaging and physiology (h-index 74) and over 30 years of experience as PCI operator, he regularly lectures and performs live cases at major scientific and educational meetings. He is a recipient of the European Society of Cardiology (ESC) Silver Medal and the Andreas Grüntzig Award for his contributions to the fiedl fo Interventional Cardiology. Main areas of expertise include complex PCI, intracoronary diagnostics and functional coronary angiography. His track record in coronary physiology comprises being investigator on pioneer FFR trials like DEFER (1998), collaborator with Justin Davies in the validation and clinical implementation of iFR, and developer of new tools for the assessment of coronary microcirculation. Editorial roles include Deputy Editor EHJ, Advisory Editor Eurointervention, editor of the textbooks “Coronary Stenosis: Imaging, Structure and Physiology” and “Physiological Assessment of Coronary Stenoses and the Microcirculation". Recent board positions include EAPCI board / Education Committee Chair, ESC WG Coronary Pathophysiology and Microcirculation, EuroCTO Board. Recent trials as Principal Investigator include ADVISE II, DEFINE FLAIR, SYNTAX II, PIONEER IV, Cerebral-Coronary-Connection (C3), DCR4Contrast, INOCA LongCovid and AID ANGIO. Additional interests are philosophy and music.

Laurie-Anne Boivin-Proulx is currently completing a Master in Interventional Cardiology and a PHD at the Hospital Clinical San Carlos, Madrid, with the goal of becoming a clinician-researcher with an interest in coronary physiology, microcirculation and women’s heart health. After her doctorate in medicine at the University of Sherbrooke (2016), she completed her residency in internal medicine (2020) and Cardiology (2023) at the University of Montreal, followed by a fellowship in Interventional Cardiology at the University of Ottawa Heart Institute (2023). In addition to her medical training, she also completed a Master of Sciences (MSc) in Epidemiology at Harvard T.H. Chan of Public Health (2021).

Dr Nieves Gonzalo is a Consultant Interventional Cardiologist at Clinico San Carlos University Hospital, Madrid, Spain. She obtained her Specialist Certification in Cardiology after training at Clinico San Carlos University Hospital in Madrid. Subsequently, she underwent a research fellowship at Thoraxcenter, Erasmus University Rotterdam (The Netherlands) focused mainly in intracoronary imaging and bioabsorbable stents. In 2010 she obtained her PhD with the thesis “Optical coherence tomography for the assessment of coronary atherosclerosis and vessel response after stent implantation”. Her track record includes over 170 articles indexed in PubMed, as well as book chapters in Interventional Cardiology textbooks. Recent research projects as principal investigator includes studies about neoatherosclerosis, vessel injury and healing after stent implantation and patterns of calcification in coronary disease. Dr Gonzalo is a dedicated educationalist with involvement in many areas of complex PCI. In 2022, Dr Gonzalo was appointed as a course director for EuroPCR, she also serves as a deputy editor of EuroIntervention, and as a co-chair of the European Association of Percutaneous Cardiovascular Interventions (EAPCI) Scientific Documents and Initiatives Committee.

Dr Tim Schäufele is an interventional cardiologist with special interest in CTOs, coronary physiology and calcified lesions. He is owner of Kardiologie-Innenstad Bern private practice and Interventional Cardiologist at Lindenhofspital Bern. Prior to this, he served as Head of Cathlab and Interventional Cardiology at Robert-Bosch-Krankenhaus Stuttgart, after serving as a Research Fellow in Cardiac Magnetic Imaging at the Department of Cardiology University Heidelberg. Dr Schäufele is a Co-Founding Member of Transradial Workingroup German Cardiac Society, a Board Member of the Interventional Working Group of the German Cardiac Society, and a Full Member EuroCTO Club.

Dr Adrián Jerónimo is an Interventional Cardiology fellow at Hospital Clínico San Carlos in Madrid (Spain). He studied Medicine at Universidad Complutense de Madrid and completed his General Cardiology training at Hospital Clínico San Carlos. He has collaborated in several research projects, including the AID ANGIO study, in which he plays a principal role. His main areas of interest are complex PCI, coronary physiology and intravascular imaging, being part of the CTO programme at Hospital Clínico San Carlos. In addition, he will be finishing his PhD in infective endocarditis and TAVI by the end of 2024.

Alejandro Travieso was born in Gran Canaria (Canary Islands, Spain), he got his degree in Medicine at the Universidad de Las Palmas de Gran Canaria in 2014, including a 1-year stage at La Sapienza University in Rome as part of the Erasmus program. Later, he specialized in Cardiology at Hospital Clínico San Carlos in Madrid. From 2020 to 2022, he was a fellow in the Interventional Cardiology unit at Hospital Clinico San Carlos. Since January 2023 he is performing a fellowship in structural interventions at Rigshospitalet (Copenhagen, Denmark). He has collaborated in several research projects, such as the Cerebral Coronary Connection study (C3), in which he had a principal role, and the ongoing AID-Angio study. In addition, he will be finishing his PhD in coronary interventions and physiology by the end of 2024. His main areas of expertise are complex PCI, coronary physiology and intravascular imaging.

Prof. Alexander Jánosi is an interventional cardiologist and currently Head of the Cath Lab and Head of the Structural Heart and Aortic Disease Program at the Department of Cardiology and Vascular Medicine at the University Hospital Essen. He graduated from medical school at the University of Düsseldorf in 2003 and was board certified in internal medicine in 2010, in intensive care medicine in 2011 and in cardiology in 2013, as well as in vascular medicine and in heart failure in 2020. His clinical interest and research include complex PCI, intravascular imaging, coronary physiology, aortic diseases (TEVAR, TAVI) and structural interventions. Prof. Jánosi is the Principal Investigator for the DEFINE-GPS trial at the University Hospital Essen.

Dr Asad Shabbir is an Interventional Cardiology Registrar at the John Radcliffe Hospital, Oxford and is also an Honorary Clinical Research Fellow at the William Harvey Research Institute, Queen Mary University of London, where he is completing his PhD. He completed his interventional cardiology fellowship at Hospital Clinico San Carlos, Madrid, Spain. Asad has an interest in complex coronary interventions, CTO PCI, and translational basic science.

Dr Giuseppe Colletti is a specialist in interventional cardiology at the Clinique Saint-Joseph in Arlon, Belgium where his focus is on developing and handling the complex PCI program. He did a fellowship in interventional cardiology at Hôpital Jolimont in La Louvrière, focusing on complex coronary lesions treatment with particular regards to calcified lesions, as well as at the Centre Hospitalier Universitaire de Liège – Sart Tilman. He graduated from medical from the University of Palermo on 2010 and he specialized in cardiology at the University of Sassari in 2016. Dr Colletti has been a published author in peer-reviewed journals and is planning on publishing more in the future as he has been increasingly involved in clinical research.

Dr. Salvatore Brugaletta is a Senior Consultant Interventional Cardiologist with a large experience in coronary and structural heart disease (Intracoronary imaging, INOCA, complex heart disease, left main, bifurcation, STEMI, cardiogenic shock, TAVI, etc). Highly skilled in Clinical Research, Medical Education and Medical Devices with strong commitment inside medical communities. Two PhD focused on interventional cardiology from Erasmus University (Rotterdam, The Netherlands) and Sacred Heart University (Rome, Italy). He has authored around 380 manuscripts published in the peer-reviewed literature. Clinically, his interests include: preventive cardiology, acute coronary syndrome / angina, drug eluting metallic and bioresorbable stents, invasive coronary imaging and physiology and TAVI (Transcatheter aortic valve implantation).

Dr Tim Schäufele is an interventional cardiologist with special interest in CTOs, coronary physiology and calcified lesions. He is owner of Kardiologie-Innenstad Bern private practice and Interventional Cardiologist at Lindenhofspital Bern. Prior to this, he served as Head of Cathlab and Interventional Cardiology at Robert-Bosch-Krankenhaus Stuttgart, after serving as a Research Fellow in Cardiac Magnetic Imaging at the Department of Cardiology University Heidelberg. Dr Schäufele is a Co-Founding Member of Transradial Workingroup German Cardiac Society, a Board Member of the Interventional Working Group of the German Cardiac Society, and a Full Member EuroCTO Club.

Alejandro Travieso was born in Gran Canaria (Canary Islands, Spain), he got his degree in Medicine at the Universidad de Las Palmas de Gran Canaria in 2014, including a 1-year stage at La Sapienza University in Rome as part of the Erasmus program. Later, he specialized in Cardiology at Hospital Clínico San Carlos in Madrid. From 2020 to 2022, he was a fellow in the Interventional Cardiology unit at Hospital Clinico San Carlos. Since January 2023 he is performing a fellowship in structural interventions at Rigshospitalet (Copenhagen, Denmark). He has collaborated in several research projects, such as the Cerebral Coronary Connection study (C3), in which he had a principal role, and the ongoing AID-Angio study. In addition, he will be finishing his PhD in coronary interventions and physiology by the end of 2024. His main areas of expertise are complex PCI, coronary physiology and intravascular imaging.

Dr Asad Shabbir is an Interventional Cardiology Registrar at the John Radcliffe Hospital, Oxford and is also an Honorary Clinical Research Fellow at the William Harvey Research Institute, Queen Mary University of London, where he is completing his PhD. He completed his interventional cardiology fellowship at Hospital Clinico San Carlos, Madrid, Spain. Asad has an interest in complex coronary interventions, CTO PCI, and translational basic science.

Dr Breda Hennessey graduated from the Third Faculty of Medicine in Charles University in Prague. Following this, she returned to Ireland to complete her general medical and higher specialist cardiology training. In 2019, she was awarded the Brian McGovern Scholarship by the Irish Cardiac Society, and this allowed her to commence her subspecialty training in Interventional Cardiology at Hospital Clínico San Carlos in Madrid. She completed a two-year coronary interventional fellowship, with a focus on intracoronary imaging, invasive physiology and ultra-low dose contrast intervention. Following completion of her coronary training, she undertook a further fellowship in structural intervention, also at Hospital Clínico San Carlos. In addition to her clinical work, she has been involved in various research projects pertaining to ultra-low dose contrast PCI, investigating the impact of new technologies in reducing contrast burden in complex PCI . She has authored and co-authored a number of research articles, book chapters and has contributed to the European association of Percutaneous Cardiovascular Interventions textbook. During her time at Hospital Clinico San Carlos, she completed a Masters in Interventional Cardiology and is currently undertaking a PHD at the Complutense University of Madrid with a focus in ultra-low dose contrast PCI. Throughout her fellowship, she regularly took part in the preparation and delivery of educational courses, both at Hospital Clinico San Carlos and in collaboration with other tertiary referral centres and international cardiology societies in Spain, the UK and the UAE.

Dr Dejan Milasinovic is an interventional cardiologist at the Department of Cardiology, Clinical Center of Serbia. He is also an Assistant Professor at Faculty of Medicine, University of Belgrade. His main research interests focus in the fields of the invasive treatment of acute coronary syndromes and complex coronary interventions, with an emphasis on bifurcation PCI and intracoronary guidance. In 2016, Dr Milasinovic received the EuroPCR 2016 Best Abstract award, for a work on the timing of invasive coronary intervention in patients with non-ST-segment elevation myocardial infarction. He is a member of European Association of Percutaneous Cardiovascular Interventions (EAPCI) and has served as program committee member of the annual EuroPCR conference. Dr Milasinovic also serves on the editorial boards of EuroIntervention (editorial consultant) and PCRonline and is the Chair of the EAPCI Young committee.

Prof Javier Escaned is Head of Section (Interventional Cardiology Section) at Hospital Clinico San Carlos / Complutense University (Madrid, Spain). He trained in the United Kingdom as Specialist in Cardiology and obtained his PhD in The Netherlands. Author of >600 indexed scientific articles on interventional cardiology, imaging and physiology (h-index 74) and over 30 years of experience as PCI operator, he regularly lectures and performs live cases at major scientific and educational meetings. He is a recipient of the European Society of Cardiology (ESC) Silver Medal and the Andreas Grüntzig Award for his contributions to the fiedl fo Interventional Cardiology. Main areas of expertise include complex PCI, intracoronary diagnostics and functional coronary angiography. His track record in coronary physiology comprises being investigator on pioneer FFR trials like DEFER (1998), collaborator with Justin Davies in the validation and clinical implementation of iFR, and developer of new tools for the assessment of coronary microcirculation. Editorial roles include Deputy Editor EHJ, Advisory Editor Eurointervention, editor of the textbooks “Coronary Stenosis: Imaging, Structure and Physiology” and “Physiological Assessment of Coronary Stenoses and the Microcirculation". Recent board positions include EAPCI board / Education Committee Chair, ESC WG Coronary Pathophysiology and Microcirculation, EuroCTO Board. Recent trials as Principal Investigator include ADVISE II, DEFINE FLAIR, SYNTAX II, PIONEER IV, Cerebral-Coronary-Connection (C3), DCR4Contrast, INOCA LongCovid and AID ANGIO. Additional interests are philosophy and music.

Dr Adrián Jerónimo is an Interventional Cardiology fellow at Hospital Clínico San Carlos in Madrid (Spain). He studied Medicine at Universidad Complutense de Madrid and completed his General Cardiology training at Hospital Clínico San Carlos. He has collaborated in several research projects, including the AID ANGIO study, in which he plays a principal role. His main areas of interest are complex PCI, coronary physiology and intravascular imaging, being part of the CTO programme at Hospital Clínico San Carlos. In addition, he will be finishing his PhD in infective endocarditis and TAVI by the end of 2024.

Dr Asad Shabbir is an Interventional Cardiology Registrar at the John Radcliffe Hospital, Oxford and is also an Honorary Clinical Research Fellow at the William Harvey Research Institute, Queen Mary University of London, where he is completing his PhD. He completed his interventional cardiology fellowship at Hospital Clinico San Carlos, Madrid, Spain. Asad has an interest in complex coronary interventions, CTO PCI, and translational basic science.

Dr Breda Hennessey graduated from the Third Faculty of Medicine in Charles University in Prague. Following this, she returned to Ireland to complete her general medical and higher specialist cardiology training. In 2019, she was awarded the Brian McGovern Scholarship by the Irish Cardiac Society, and this allowed her to commence her subspecialty training in Interventional Cardiology at Hospital Clínico San Carlos in Madrid. She completed a two-year coronary interventional fellowship, with a focus on intracoronary imaging, invasive physiology and ultra-low dose contrast intervention. Following completion of her coronary training, she undertook a further fellowship in structural intervention, also at Hospital Clínico San Carlos. In addition to her clinical work, she has been involved in various research projects pertaining to ultra-low dose contrast PCI, investigating the impact of new technologies in reducing contrast burden in complex PCI . She has authored and co-authored a number of research articles, book chapters and has contributed to the European association of Percutaneous Cardiovascular Interventions textbook. During her time at Hospital Clinico San Carlos, she completed a Masters in Interventional Cardiology and is currently undertaking a PHD at the Complutense University of Madrid with a focus in ultra-low dose contrast PCI. Throughout her fellowship, she regularly took part in the preparation and delivery of educational courses, both at Hospital Clinico San Carlos and in collaboration with other tertiary referral centres and international cardiology societies in Spain, the UK and the UAE.

Dr Dejan Milasinovic is an interventional cardiologist at the Department of Cardiology, Clinical Center of Serbia. He is also an Assistant Professor at Faculty of Medicine, University of Belgrade. His main research interests focus in the fields of the invasive treatment of acute coronary syndromes and complex coronary interventions, with an emphasis on bifurcation PCI and intracoronary guidance. In 2016, Dr Milasinovic received the EuroPCR 2016 Best Abstract award, for a work on the timing of invasive coronary intervention in patients with non-ST-segment elevation myocardial infarction. He is a member of European Association of Percutaneous Cardiovascular Interventions (EAPCI) and has served as program committee member of the annual EuroPCR conference. Dr Milasinovic also serves on the editorial boards of EuroIntervention (editorial consultant) and PCRonline and is the Chair of the EAPCI Young committee.

Dr Marco Lombardi is an interventional cardiology fellow at the Hospital Clinico San Carlos/Complutense University (Madrid, Spain) from the Catholic University of the Sacred Heart (Rome, Italy). He obtained his medical degree at the Campus Bio-Medico University in 2018 (Rome, Italy), and he trained as a research fellow at the VCU Pauley Heart Center (Richmond, USA) before starting his PhD degree that he is completing at the University of Genoa (Genoa, Italy).

Dr Justin Davies is a honorary 
interventional cardiologist at Hammersmith Hospital, Imperial College NHS Trust, London. After training at Imperial College, he won a prestigious BHF research fellowship to study arterial haemodynamics. Since then he has continued to
work on the development of mathematical algorithms to aid understanding of large artery physiology and to develop new tools to assess arterial disease. The holder of several patents,
he has published widely in the field of hypertension, coronary and large artery physiology and is the winner of many national and international awards. He has several international collaborations, and is the developer of iFR and the co-principal investigator of the ADVISE studies, the DEFINE-FLAIR, ORBITA and DEFINE-PCI studies. Justin also has an interest in renal denervation, and has lead the first-in-man studies to evaluate the safety of this technique to patients with chronic systolic heart failure (REACH studies).