Como usar fisiologia invasiva e imagem com co-registro para planejar e orientar PCI complexa

Daniel Chamié, MD, PhD concluded his interventional cardiology training at Dante Pazzanese Institute of Cardiology in Sao Paulo, Brazil, in 2009. Between 2010 and 2012 he served as research associate at the intravascular imaging core lab at University Hospitals, Case Medical Center, Cleveland, OH, where he advanced his knowledge in the use of intracoronary physiology and imaging, particularly OCT. Upon his return to Brazil, practiced as an interventional cardiologist at Dante Pazzanese Institute, developing experience in complex PCI and intracoronary imaging and physiology. Over the last decade, he also has been involved in clinical research on the assessment of novel drug-eluting stents and bioresorbable scaffolds and was the leading investigator of the iSIGHT trial, proposing an algorithmic approach in the use of intravascular imaging to guide PCI. In parallel with his clinical activities, he served as director of the OCT core lab at the Cardiovascular Research Center from 2012 to 2020. During this time, he developed OCT analysis methods for several studies on novel devices (e.g. bioresorbable scaffolds, drug-eluting stents, specialty balloons) in various clinical scenarios (e.g. stable CAD, ACS, bifurcation lesions, high-bleeding risk patients, etc). Since 2022, he has practiced as the Director of Invasive Cardiovascular Imaging at the Yale School of Medicine, New Haven, CT, and is the director of the Intravascular Imaging and Physiology Core Laboratories at the Yale Cardiovascular Research Group.

Dr Ricardo Petraco is a NIHR Lecturer in interventional Cardiology at Imperial College London, performing his clinical work at Hammersmith Hospital. He has been working with coronary physiology at Imperial since 2010 on the development of the novel instantaneous wave-Free Ratio (iFR). Dr Petraco’s work with iFR has led to the proposition of the Hybrid iFR-FFR approach and has established iFR’s close relationship with coronary flow reserve (CFR). His interests in computer programming has led to the development of a software for automated analysis of coronary haemodynamics signals which is been used by many leading centres in the world. He has also pioneered the algorithm for iFR calculation without the need for an ECG signal, an approach which is now implemented in clinical consoles. He has secured several research grants and published extensively in the field of coronary physiology. His current research interests are on the development of methodologies to assess stenosis severity in situations of haemodynamic instability and on the understanding of how medical therapies modulate coronary resistance and flow. Clinically, his interests also include the use of intravascular imaging modalities to optimise PCI and has been engaged in IVUS training for cathlab staff and cardiology trainees.