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Advances in Co-registration, Coronary Physiology & Intra Coronary Imaging

14 June

4:00 AM America/New_York

7H 20M

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Advances in Co-registration, Coronary Physiology & Intra Coronary Imaging is the premier international e-Course focusing on intracoronary co-registration run by a leading and world renowned international faculty. This course specialises in coronary co-registration, and builds on the 9 years of courses which have been run and quickly established as the leading global interventional course in state-of-the-art coronary physiology and intracoronary imaging.

Speakers

Justin Davies

Dr Justin Davies is a clinical academic and consultant interventional cardiologist at the National Heart and Lung Institute, Imperial College London. After training at Imperial College, he won a prestigious BHF research fellowship to study arterial haemodynamics. Since then he has continued to work on the development of mathematical algorithms to aid understanding of large artery physiology and to develop new tools to assess arterial disease. The holder of several patents, he has published widely in the field of hypertension, coronary and large artery physiology and is the winner of many national and international awards. He has several international collaborations, and is the developer of iFR and the co-principal investigator of the ADVISE studies, the DEFINE-FLAIR, ORBITA and DEFINE-PCI studies. Justin also has an interest in renal denervation, and has lead the first-in-man studies to evaluate the safety of this technique to patients with chronic systolic heart failure (REACH studies).

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Javier Escaned

Prof Javier Escaned is Head of Interventional Cardiology Section at Hospital Clinico San Carlos (Madrid, Spain). He trained as a cardiologist the United Kingdom before moving to the Thoraxcenter / Rotterdam (The Netherlands), where he obtained his PhD degree in 1994. A skilled interventionalist with over 30 years of experience, he regularly serves as live case operator and educationalist in global events like EuroPCR, TCT or the ESC Congress. He is author of over 400 PubMed indexed scientific articles (h-index 67) on topics that include complex PCI in multivessel disease (principal investigator of SYNTAX II study), left main and chronic total occlusions, and secondary revascularization. His track record in coronary physiology includes being investigator on pivotal FFR trials like DEFER (1998), collaborator with Justin Davies in the validation and clinical implementation of iFR (since 2010), and developer of new methods for the assessment of microvascular and non-obstructive coronary disease. Recent / ongoing trials as Co-PI include ADVISE, ADVISE II, DEFINE FLAIR and ABSORB II PHYSIOLOGY, being investigator also in ILUMIEN I and IV, COMBINE and other studies on coronary imaging. He is currently Deputy Editor for Interventional Cardiology of the European Heart Journal, as well as editor of two large textbooks: “Coronary Stenosis. Imaging, Structure and Physiology”, (co-editor Patrick Serruys) and “Physiological Assessment of Coronary Stenoses and the Microcirculation) (co-editor Justin Davies). Current or recent board positions in scientific societies include EuroPCR, EAPCI, EuroCTO and the ESC Working Group of Coronary Pathophysiology and Microcirculation. Some of his additional interests are philosophy, education and music.

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Carlo Di Mario

Prof Carlo Di Mario is Professor of Cardiology at the University of Florence and Director of the Structural 
Interventional Cardiology Division of the University Hospital Careggi, Florence, Italy. Previous posts included 15 years as 
Professor of Clinical Cardiology at Imperial College of Sciences,
 Medicine & Technology, London and Consultant Cardiologist at 
the Royal Brompton Hospital. He also practiced at the San 
Raffaele University Hospital, Milan, Italy. He trained in Cardiology at the 
University of Padova, Italy, but he soon moved for interventional training at the Thoraxcentre of Rotterdam, the Netherlands, where he also completed a PhD in Intracoronary Ultrasound Imaging and Doppler. Despite his teaching, research and administrative commitments, he maintains an active clinical involvement performing more than 100 PCI per year with special interest in the treatment of calcified lesions, chronic total occlusions, bifurcations, and diffuse disease. He is a regular TAVI operator and certified implanter for the Medtronic Evolut R and Edwards Sapien 3 transcatheter aortic valves. He participated in more than 260 MitraClip implantations in London and Florence and has recently started direct annuloplasty with the CardioBand. Professor Di Mario pioneered the use of intracoronary Doppler, pressure measurement, intravascular ultrasound, optical coherence tomography, and near infrared spectroscopy. He was PI of the OPTICUS trial, failing to demonstrate superiority of IVUS guided stenting, and of the Lipid Rich Plaque study, due to report at TCT 2018. He was Principal Investigator of the DESTINI trial, using Doppler CRF to identify lesions in need of stenting, and of the CARESS in AMI trial, a large multicentre trial showing that patients who receive fibrinolytic therapy for ST-elevation myocardial infarction benefit from early angioplasty. This trial and a subsequent meta-analysis have led to a change in the European Society of Cardiology and AHA/ACC Guidelines for treatment of STEMI patients. He cooperated with Dr Davies to the validation of iFR to assess lesion severity and discriminate the contribution of individual lesions, and with Dr Lyon in the intracoronary delivery of SERCA-2 genes via adenoviral vectors in the CUPID2 trial. He was the main recruiter of the DISRUPT-I-CAD study and is PI of the DISRUPT-II trial, both pioneering the use of coronary lithotripsy for calcified coronary lesions.

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Andrew Sharp

Dr Sharp qualified from Edinburgh Medical School in 1998. He was appointed as a Consultant Cardiologist at the Royal Devon and Exeter Hospital in 2011 and Honorary Associate Professor by the University of Exeter in 2018 before moving to the University Hospital of Wales in the summer of 2019. He conducted his early training at the Royal Infirmary of Edinburgh, before moving to London for his senior clinical training. He completed the prestigious Milan-Imperial Interventional Cardiology Fellowship programme, having spent a year in San Raffaele and Columbus Hospitals, Milan, Italy, under the tutelage of Professor Antonio Colombo. He also spent three years training in interventional cardiology at St Mary’s Hospital and The Hammersmith Hospital (Imperial College Hospitals) in London. Dr Sharp was awarded an MD postgraduate research degree from the University of Edinburgh for his work on the hypertensive heart and led a large research programme at the Royal Devon and Exeter Hospital, which he is now establishing in Wales. He has been Principal Investigator in more than 30 ethically-approved research trials since 2012 and has published extensively. He has an international reputation for leading the development of device-based treatments for hypertension (in particular that of renal denervation) and pulmonary embolism, as well as the advancement of intracoronary imaging and physiology.

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Nigel Jepson

Associate Professor Nigel Jepson BMed Sci, MB BS, FRACP, FCSANZ, FSCAI is Director of the Cardiac Catheterization Laboratories at the Eastern Heart Clinic and Director of the Clinical Trials Unit at the Prince of Wales Public Hospital in Sydney, Australia. He holds the position of Conjoint Professor at the University of New South Wales. Associate Professor Jepson trained in Tasmania and completed clinical and cardiac interventional training at Harefield Hospital in London and the Eastern Heart Clinic in Sydney. He is a high volume interventionalist, practicing over the last 20 years with a specific interest in bifurcation and left main-stem disease, new stent technology and intra- coronary imaging. He has performed more than 10,000 coronary procedures and heads a transcatheter aortic valve replacement program. Associate Professor Jepson is a regular invited speaker, faculty member and live-case operator for interventional forums and meetings in USA, Europe, Asia and Australasia (including EuroPCR, TCTAP, C3, AICT, ANZET, Nanjing CBS, Malaysia Live, SCAI and the European Bifurcation Club). He is an author or co-author of more than 80 published papers and principal investigator on 30 major international, multicentre trials.

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Nieves Gonzalo

Dr Nieves Gonzalo is Consultant Interventional Cardiologist at the Interventional Cardiology Department at Clinico San Carlos University Hospital in Madrid. She obtained her Specialist Certification in Cardiology after training at Clinico San Carlos University Hospital in Madrid. Subsequently, she underwent a research fellowship at Thoraxcenter, Erasmus University Rotterdam (The Netherlands) under the supervision of Professor Patrick Serruys, focused mainly in intracoronary imaging and bioabsorbable stents. In 2010 she obtained her PhD with the thesis “Optical coherence tomography for the assessment of coronary atherosclerosis and vessel response after stent implantation”. Her track record includes over 170 articles indexed in PubMed, as well as book chapters in Interventional Cardiology textbooks. Recent research projects as principal investigator includes a study about the assessment of neoatherosclerosis and its clinical impact in patients with restenosis (RIBS IV and V OCT substudy) and research regarding vessel injury and healing evaluation with different stent platforms evaluated with OCT (VISTA study). Dr Gonzalo is a dedicated educationalist with involvement in many areas of complex PCI, serving currently as Deputy Editor for Eurointervention and Committee Member of EuroPCR.

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Niels Van Royen

Niels van Royen is an interventional cardiologist and Head of Department of Cardiology at the Radboud University Medical Center, Nijmegen, the Netherlands. He has a background in pre-clinical research and is head of a research group on translational research in repair mechanisms in ischemic heart disease. Also he is principal investigator of several multi-center clinical trials like the TRANSIENT, COACT, REDUCE-MVI and iMODERN. These trials focus on timing of interventional procedures as well as the use of intra-coronary physiology to guide interventional procedures both in stable coronary artery disease as well as acute coronary syndromes.

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Bon-Kwon Koo

Dr. Bon-kwon Koo is a professor of Seoul National University, director of cardiovascular center and chair in Cardiology Division of Seoul National University Hospital, Seoul, Korea. Dr. Koo graduated Yonsei University, Seoul, Korea and was a visiting scholar at Stanford University previously and worked with Professor Peter J Fitzgerald and Professor William Fearon. Dr. Koo is an interventional cardiologist and his main research interest is imaging and physiology of coronary artery disease. Dr. Koo is a principal investigator of many domestic and international studies. He has published more than 400 papers in major journals. He was a course director of TCT-AP and is a course co-director of ENCORE course. He has performed series of studies on bifurcation lesions and coronary physiology/imaging which provided important insights in this field. His recent researches on non-invasive hemodynamic assessment using coronary CT angiography and computational fluid dynamics enables the assessment of FFR without invasive procedures and has started a new chapter in the diagnosis of coronary artery disease. This innovation has now been expanded to non-invasive treatment planner and non-invasive assessment for the risk of ACS.

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Morton Kern

Dr. Kern is Chief of Medicine, VA Long Beach Health Care System, Professor of Medicine, University California, Irvine. He continues to perform and teach cardiac catheterization and PCI. Dr. Kern is ABIM Certified in Internal Medicine, Cardiovascular Diseases and Interventional Cardiology and is a past president and now a Master Fellow of the SCAI. His research interests in coronary blood flow, intravascular physiology, intravascular ultrasound, vulnerable plaque and evaluation of cardiovascular hemodynamics. He has authored several textbooks, notably The Cardiac Catheterization Handbook, 6th ed. and its companion The Interventional Cardiac Cath Handbook, 4th ed.

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Tim van de Hoef

Tim van de Hoef, MD, PhD, FESC, is an interventional cardiology fellow at the Amsterdam UMC - VU Medical Center (Amsterdam, The Netherlands). He has been involved in intracoronary physiology research since 2010, and his research has covered the wide spectrum of intracoronary physiology assessed by means of invasive coronary pressure and flow measurements, ranging from functional stenosis severity appraisal to assessment of microvascular function in both stable coronary artery disease and acute coronary syndromes. He obtained a PhD (Cum Laude) in invasive coronary physiology in 2015. He has (co-)authored over 90 papers on the topic of coronary physiology, and his recent research has focused on the use of basal conditions for the assessment of epicardial stenosis severity, and the combined assessment of epicardial and microvascular disease to optimize diagnosis and risk-stratification in ischemic heart disease.

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Habib Samady

Dr. Habib Samady trained in general cardiology, nuclear cardiology and interventional cardiology at Yale University. He joined Emory University in 2005. In 2009, he became Professor of Medicine and in 2011, Director of Interventional Cardiology at Emory University. He has received several outstanding teaching awards. Dr. Samady has an actively funded clinical and translational research program to investigate: - Hemodynamic mechanisms associated with progression of human coronary atherosclerosis - Evaluation of pharmaceutical agents for treatment of coronary microvascular disease, endothelial dysfunction, coronary vasospasm and non obstructive atherosclerosis - Biomechanics of permanent and Bioresorbable coronary vascular devices Dr. Samady is Deputy Editor of JACC Cardiovascular Interventions, is on the editorial board of numerous cardiovascular journals, and is extensively published.

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Manesh Patel

Manesh Patel is the Chief of the Division of Cardiology and the Division of Clinical Pharmacology. His clinical interests include diagnostic and interventional coronary angiography, peripheral angiography and endovascular intervention. His is involved in several clinical trials involving patients with cardiovascular disease and in cardiac imaging. He is also the Chair of the American College of Cardiology Task Force for Appropriate Use Criteria for Cardiovascular Procedures and is Chair of the American Heart Association Diagnostic and Interventional Cath Committee. Patel's interest in cardiac imaging, quality of care, cardiac devices is also evident in his research. His integration of these efforts into his roles at Duke was recognized in 2010 when he received the prestigious Duke Cardiology Fellowship Mentor Award. In 2011, Dr. Patel was named the endowed John Bush Simpson Assistant Professor of Cardiology. In 2013, Dr. Patel received the Robert M. Califf Faculty clinical research Award. Currently, Dr. Patel is leading an effort to redesign the delivery of care to patients undergoing invasive catheterization procedures in the health system with a specific aim of measure and providing individualized, patient centered, innovative, and efficient care.

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Sukhjinder Nijjer

Dr. Nijjer is a Consultant Cardiologist and Senior Clinical Lecturer at Imperial College London. He works at both the Hammersmith Hospital and Chelsea & Westminster Foundation NHS Trust, as well as leading private Hospitals in London including the Wellington and Cromwell Hospitals. He is the President-elect of the Cardiology Section of the Royal Society of Medicine, and he was selected as an Emerging Leader for the British Cardiovascular Society. He specialises in coronary intervention and focused his clinical practice in the management of ischaemic heart disease. His practice encompasses all aspects of cardiology. In his PhD research, funded by the Medical Research Council (UK) and awarded by Imperial College he developed of new intracoronary physiology techniques, specifically iFR and iFR-pullback and Co-registration. He has published almost 100 peer-reviewed papers in respected journals, including the New England Journal of Medicine and The Lancet. He has also written several books.

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Yu Cao

Works at Third Xiangya Hospital of Central South University, Changsha, China. Features in 1 video on Wondr Medical. Yu Cao generally speaks on Coronary Interventions, Coronary Optical Coherence Tomography (OCT), and Intravascular Ultrasound (IVUS).

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Amir Lerman

Prof Amir Lerman is a professor of medicine and a consultant in the cardiovascular division at the Mayo graduate school of Medicine. Prof Lerman serves as an associate chair and the director for research for the cardiovascular division and the director of the Mayo cardiovascular research center. Prof Lerman graduated from the Technion school of Medicine in Haifa Israel and completed his training in internal medicine, cardiovascular diseases and invasive cardiology at the Mayo Clinic. Prof Leman interest is, coronary physiology and imaging and innovation in cardiovascular disease as well as regenerative medicine. Prof Lerman published more than 600 manuscripts, book chapters and reviews; the NIH, AHA, and several foundations support his research.

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Christopher Cook

Dr Christopher Cook is a Medical Research Council Clinical Fellow at Imperial College London, undertaking a PhD in coronary physiology under the supervision of Dr Justin Davies. He studied Medicine at University College London (UCL) and graduated with Distinction (Clinical Medicine and Clinical Sciences) in his final MBBS Examinations in 2009. He achieved a First Class (Honours) Bachelor of Science degree in Physiology undertaking a period of research at The Hatter Cardiovascular Institute. He was awarded ‘The Dean’s List’ for outstanding performance in the Faculty of Life Sciences. In total he was awarded 17 prizes including the prestigious Gold Medal Medicine (proxime accessit). In 2014, he was awarded the Imperial Valve and Cardiovascular Course Young Investigator Prize. In 2015 he was awarded the inaugural EuroPCR’s Got Talent Award. In 2017 he was elected onto the EuroPCR Clinical Programme Committee.

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Chris Gale

Chris is Professor of Cardiovascular Medicine, Consultant Cardiologist at Leeds General Infirmary, UK. Qualifying in medicine at the London Hospital Medical College and obtaining a BSc in Psychology, he worked as a Junior Doctor at the Royal London Hospital. After obtaining MRCP, he completed a MRC funded Ph.D in molecular biology. Speciality training was undertaken principally at the Leeds General Infirmary, where he was a Walport and later a NIHR Academic Clinical Lecturer, then achieving a NIHR Clinician Scientist Award and NIHR Clinical Trials Fellowship. As Consultant Cardiologist at Leeds General Infirmary, he practices clinical cardiology with interests in general cardiology and heart failure. He also practices at The Duchy BMI, Harrogate, UK https://www.bmihealthcare.co.uk/consultants/chris-gale#gdpr-out Chris' research incorporates the efficient use of observational and randomised data to deliver population-based studies of cardiovascular care and outcomes. He holds research awards from the NIHR, BHF and Horizon 2020, and has published >220 articles in peer-reviewed journals. He is a FRCP, FESC and member of the British Cardiovascular Society. He has been a member of the Myocardial Ischaemic National Audit Project Steering Group for over a decade. Chris holds a number of leadership positions including Chair of Data Science Group of the EuroHeart project https://www.escardio.org/Research/euroheart, Chair of the European Society of Cardiology Quality Indicator Committee and member of the NICE Indicator Advisory Committee https://www.nice.org.uk/get-involved/meetings-in-public/indicator-advisory-committee-iac/iac-members. He is Deputy Editor of EHJ Quality of Care and Clinical Outcomes https://academic.oup.com/ehjqcco and Chairs several Data Monitoring Committee for randomised clinical trials. Chris can be followed on Twitter where he regularly tweets about cardiology, his research and life in general! @cpgale3 https://twitter.com/cpgale3

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Agendas

Advances in Co-registration, Coronary Physiology & Intra Coronary Imaging

Advances in Co-registration, Coronary Physiology & Intra Coronary Imaging is the premier international e-Course focusing on intracoronary...
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4:00 AM - 4:05 AM America/New_York

Welcome and introductions

With Justin Davies and Javier Escaned

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4:05 AM - 4:30 AM America/New_York

Research News & Updates

With Javier Escaned, Justin Davies, Andrew Sharp, and Carlo Di Mario

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4:30 AM - 4:50 AM America/New_York

Core essentials of understanding coronary physiology

With Justin Davies

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4:50 AM - 5:10 AM America/New_York

Core essentials of understanding IVUS

With Andrew Sharp

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5:10 AM - 5:30 AM America/New_York

Core essentials of understanding Co-registration

With Nigel Jepson

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5:30 AM - 6:10 AM America/New_York

Live case demonstration: Co-registration iFR Transmission from Hospital Clinico San Carlos, Madrid

With Javier Escaned, Nieves Gonzalo, Justin Davies, Andrew Sharp, Carlo Di Mario, and Niels Van Royen

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6:10 AM - 6:25 AM America/New_York

When should we be using IVUS & Coronary Physiology in clinical practice?

With Bon-Kwon Koo

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6:30 AM - 9:30 AM America/New_York

Break

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9:30 AM - 9:35 AM America/New_York

Welcome and introductions

With Justin Davies and Javier Escaned

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9:35 AM - 9:40 AM America/New_York

AM live case review / update

With Carlo Di Mario, Javier Escaned, and Nieves Gonzalo

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9:40 AM - 10:00 AM America/New_York

Practical tips and tricks of making good coronary physiology measurements

With Morton Kern

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10:00 AM - 10:20 AM America/New_York

Practical tips and tricks of making good IVUS measurements

With Carlo Di Mario

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10:20 AM - 10:40 AM America/New_York

Practical tips and tricks for making good co-registration measurements

With Andrew Sharp

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10:40 AM - 11:10 AM America/New_York

My best coronary physiology learning cases

With Tim van de Hoef and Habib Samady

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11:10 AM - 11:40 AM America/New_York

My best IVUS learning cases

With Carlo Di Mario

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11:40 AM - 12:00 PM America/New_York

Integrated approach to PCI decision-making

With Manesh Patel

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4:00 AM - 4:05 AM America/New_York

Welcome and introductions

With Justin Davies and Javier Escaned

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4:05 AM - 4:10 AM America/New_York

Overview and review of Day 1

With Justin Davies and Javier Escaned

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4:10 AM - 5:00 AM America/New_York

Moving beyond the angiogram. Show me the data to support the use of coronary physiology & imaging

With Javier Escaned

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5:00 AM - 5:20 AM America/New_York

Can I measure coronary physiology in A.Fib, CHF, Pacing, Cardiogenic shock, Aortic Stenosis?

With Sukhjinder Nijjer

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5:20 AM - 5:40 AM America/New_York

Ultra Low Contrast PCI in CTOs using ChromaFlo

With Yu Cao

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5:40 AM - 6:05 AM America/New_York

Using IVUS to simplify CTO treatment

With Javier Escaned

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6:05 AM - 6:30 AM America/New_York

What has the effect of COVID-19 been on patient care?

With Chris Gale

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6:30 AM - 9:00 AM America/New_York

Break

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9:00 AM - 9:05 AM America/New_York

Welcome and introductions

With Justin Davies and Javier Escaned

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9:05 AM - 9:35 AM America/New_York

Why is the physiology negative? Integration of the coronary microcirucation to decision-making

With Amir Lerman

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9:35 AM - 10:00 AM America/New_York

DEFINE-GPS leading to full integration of coronary physiology to PCI decision-making

With Justin Davies

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10:00 AM - 10:20 AM America/New_York

Evolution of artificial intelligence in coronary physiology

With Christopher Cook

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10:20 AM - 11:20 AM America/New_York

My best co-registration cases

With Andrew Sharp and Sukhjinder Nijjer

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