Ultra-low contrast PCI
9:00 AM America/New_York
Chairmen: Javier Escaned/ Ziad Ali
A change in mindset - Javier Escaned
Intracoronary IVUS for zero- or ultralow-contrast PCI - Ziad Ali
Dynamic Coronary Roadmapping to spare contrast administration in PCI Breda Hennessey
Practical examples of IVUS-guided ultralow-contrast procedures – Jasvinder Singh
Prof Javier Escaned is Head of Interventional Cardiology Section at Hospital Clinico San Carlos (Madrid, Spain). He trained as a cardiologist the United Kingdom before moving to the Thoraxcenter / Rotterdam (The Netherlands), where he obtained his PhD degree in 1994. A skilled interventionalist with over 30 years of experience, he regularly serves as live case operator and educationalist in global events like EuroPCR, TCT or the ESC Congress. He is author of over 400 PubMed indexed scientific articles (h-index 67) on topics that include complex PCI in multivessel disease (principal investigator of SYNTAX II study), left main and chronic total occlusions, and secondary revascularization. His track record in coronary physiology includes being investigator on pivotal FFR trials like DEFER (1998), collaborator with Justin Davies in the validation and clinical implementation of iFR (since 2010), and developer of new methods for the assessment of microvascular and non-obstructive coronary disease. Recent / ongoing trials as Co-PI include ADVISE, ADVISE II, DEFINE FLAIR and ABSORB II PHYSIOLOGY, being investigator also in ILUMIEN I and IV, COMBINE and other studies on coronary imaging. He is currently Deputy Editor for Interventional Cardiology of the European Heart Journal, as well as editor of two large textbooks: “Coronary Stenosis. Imaging, Structure and Physiology”, (co-editor Patrick Serruys) and “Physiological Assessment of Coronary Stenoses and the Microcirculation) (co-editor Justin Davies). Current or recent board positions in scientific societies include EuroPCR, EAPCI, EuroCTO and the ESC Working Group of Coronary Pathophysiology and Microcirculation. Some of his additional interests are philosophy, education and music.
Dr Breda Hennessey is an interventional cardiology fellow at Hospital Clínico San Carlos. She Graduated from the Third Faculty of Medicine in Charles University in Prague. Following this ,she returned to Ireland in 2011. She completed her Internal Medicine training in 2014 and General Cardiology training in 2019 through the Royal College of Physicians in Ireland. She was awarded the Brian McGovern Scholarship by the Irish Cardiac Society in 2019 and commenced her clinical and research fellowship at Hospital Clínico San Carlos last November. She Is currently working as an assistant PI in the ongoing DCR4 contrast study, a multicentred prospective randomised study, investigating the impact of new technologies in reducing contrast burden in complex PCI . She is also involved with the complex PCI subset, including the CTO programme at Hospital Clínico San Carlos.
Dr. Singh is an Associate Professor of Medicine, Medical Director, Cardiac Catheterization Laboratory at Barnes-Jewish Hospital and Director of Interventional Cardiology. He specializes in coronary and peripheral vascular interventional procedures and spends most of his time in the cardiac catheterization laboratory. His expertise is in complex coronary intervention and also the endovascular treatment of renovascular hypertension, and peripheral arterial occlusive diseases. In addition, he has been involved in research ranging from new coronary devices to intravascular ultrasound and pressure/flow assessment of coronary vessels. He is the Principal Investigator in several high profile multicenter trials evaluating the above. He is actively involved in resident/fellow education and rotate in the coronary care unit twice a year. He has two interventional fellows per year who work closely with him during their training, he also serves as their attending in ½ day in patient clinic. He has second and third year cardiology fellows involved in clinical research protocols in the cath lab and their work has produced three instrumental abstracts/papers which in the first 12 months were presented at major cardiovascular society meetings. Dr. Singh is also the Chairman of ARCH, one of the largest Midwest Interventional Symposium.
Ziad Ali is the Director of the DeMatteis Cardiovascular Institute, Director of Investigational Interventional Cardiology, and Director of Cardio-nephrology at St Francis Hospital & Heart Center in New York. He is also Director of the Angiographic Core Laboratory at Cardiovascular Research Foundation and Associate Professor of Medicine at Columbia University Medical Center. His clinical research interests focus on the use of intravascular imaging and physiology technologies such as optical coherence tomography, intravascular ultrasound, and flow wire assessment to optimize coronary interventions, for which he has served as a Global principal investigator on a number of trials. Dr. Ali is also a recognized innovator, playing an integral role in the development of the Resting Full-Cycle Ratio (RFR) and Shockwave intravascular lithotripsy. Clinically Dr. Ali developed pioneering techniques to perform vascular interventions without contrast administration, including IVUS-guided zero-contrast PCI and OCT using saline flush media, protecting patients with advanced kidney disease from acute kidney injury and the need for dialysis.