Live case demonstration: Co-registration iFR Transmission from Hospital Clinico San Carlos, Madrid

Dr Sharp qualified from Edinburgh Medical School in 1998. He was appointed as a Consultant Cardiologist at the Royal Devon and Exeter Hospital in 2011, before moving to the University Hospital of Wales, in Cardiff, UK in the summer of 2019, where he is now Honorary Professor of Cardiology. He conducted his early training at the Royal Infirmary of Edinburgh, before moving to London for his senior clinical training. He completed the Milan-Imperial Interventional Cardiology Fellowship programme, having spent a year in San Raffaele and Columbus Hospitals, Milan, Italy, under the tutelage of Professor Antonio Colombo. He also spent three years training in interventional cardiology at St Mary’s Hospital and The Hammersmith Hospital (Imperial College Hospitals) in London. Prof Sharp was awarded an MD postgraduate research degree from the University of Edinburgh for his work on the hypertensive heart and leads a large research programme in Wales. He has an international reputation for leading the development of device-based treatments for hypertension (in particular that of renal denervation) and pulmonary embolism, as well as the advancement of intracoronary imaging and physiology.

Carlo Di Mario is Professor of Cardiology at the University of Florence and Director of the Structural 
Interventional Cardiology Division of the University Hospital Careggi, Florence, Italy. Previous posts included 15 years as Professor of Clinical Cardiology at Imperial College of Sciences, Medicine & Technology, London and Consultant Cardiologist at the Royal Brompton Hospital. Despite his teaching, research and administrative commitments, he maintains an active clinical involvement performing more than 100 PCI per year with special interest in the treatment of calcified lesions, chronic total occlusions, bifurcations, and diffuse disease. He is a regular TAVI operator and certified implanter for the Medtronic Evolut R and Edwards Sapien 3 transcatheter aortic valves. He participated in more than 160 MitraClip implantations in London and Florence and has recently started direct annuloplasty with the CardioBand. Professor Di Mario pioneered the use of intracoronary Doppler, pressure measurement, intravascular ultrasound, optical coherence tomography, and near infrared spectroscopy. He was PI of the OPTICUS trial, failing to demonstrate superiority of IVUS guided stenting, and of the Lipid Rich Plaque study, due to report at TCT 2018. He was Principal Investigator of the DESTINI trial, using Doppler CRF to identify lesions in need of stenting, and of the CARESS in AMI trial, a large multicentre trial showing that patients who receive fibrinolytic therapy for ST-elevation myocardial infarction benefit from early angioplasty. This trial and a subsequent meta-analysis have led to a change in the European Society of Cardiology and AHA/ACC Guidelines for treatment of STEMI patients. He cooperated with Dr Davies to the validation of iFR to assess lesion severity and discriminate the contribution of individual lesions, and with Dr Lyon in the intracoronary delivery of SERCA-2 genes via adenoviral vectors in the CUPID2 trial.

Prof Javier Escaned is Head of Interventional Cardiology Section at Hospital Clinico San Carlos (Madrid, Spain). He trained as a cardiologist the United Kingdom before moving to the Thoraxcenter / Rotterdam (The Netherlands), where he obtained his PhD degree in 1994. With over 30 years of experience as interventionalist, he regularly serves as live case operator and educationalist in global events. He is author of over 500 PubMed indexed scientific articles (h-index 74) on topics that include complex PCI in multivessel disease, left main and chronic total occlusions. His track record in coronary physiology includes being investigator on pivotal FFR trials like DEFER (1998), collaborator with Justin Davies in the validation and clinical implementation of iFR (since 2010), and developer of new methods for the assessment of microvascular and non-obstructive coronary disease. Editorial work includes two large textbooks (“Coronary Stenosis. Imaging, Structure and Physiology” and “Physiological Assessment of Coronary Stenoses and the Microcirculation) and editorial board positions in scientific journals. Board positions in scientific societies include EuroPCR, EAPCI, EuroCTO and the ESC Working Group of Coronary Pathophysiology and Microcirculation. Additional interest incllude music and phylosophy. He is a recipient of the ESC Silver Medal and the 2022 ESC Andreas Gruentzig Award.

Dr Justin Davies is founder and CEO of Wondr Medical, inventor of iFR, and clinical academic and consultant interventional cardiologist at the National Heart and Lung Institute, Imperial College London.

Dr Nieves Gonzalo is Consultant Interventional Cardiologist at the Interventional Cardiology Department at Clinico San Carlos University Hospital in Madrid. She obtained her Specialist Certification in Cardiology after training at Clinico San Carlos University Hospital in Madrid. Subsequently, she underwent a research fellowship at Thoraxcenter, Erasmus University Rotterdam (The Netherlands) under the supervision of Professor Patrick Serruys, focused mainly in intracoronary imaging and bioabsorbable stents. In 2010 she obtained her PhD with the thesis “Optical coherence tomography for the assessment of coronary atherosclerosis and vessel response after stent implantation”. Her track record includes over 170 articles indexed in PubMed, as well as book chapters in Interventional Cardiology textbooks. Recent research projects as principal investigator includes a study about the assessment of neoatherosclerosis and its clinical impact in patients with restenosis (RIBS IV and V OCT substudy) and research regarding vessel injury and healing evaluation with different stent platforms evaluated with OCT (VISTA study). Dr Gonzalo is a dedicated educationalist with involvement in many areas of complex PCI, serving currently as Deputy Editor for Eurointervention and Committee Member of EuroPCR.

Sa’ar Minha MD is a professor of cardiology at Tel-Aviv University, Israel, and the director of interventional cardiology at Shamir Medical Center, Be’er Yaakov in Israel- one of the largest government-owned hospitals in the country. He also serves as the secretary of the interventional cardiology working group under the Israel Heart Society. Prof. Minha earned his MD degree from Tel-Aviv University in Israel and completed an internal medicine residency and cardiology fellowship at Shamir Medical Center. His interventional cardiology fellowship was completed in 2014 at the Washington Hospital Center, affiliated with Georgetown University, Washington DC under Prof. Ron Waksman, Prof. Gus Pichard, and Prof. Lowell Satler. Prof Minha is an active speaker and an invited faculty for major international cardiology conferences and the co-author of over 110 original research publications. His main interests are complex coronary interventions combining physiology and imaging for optimizing results and outcomes, interventions for pulmonary embolism, renal denervation for treating hypertension, and interventions under mechanical circulatory support.

Dr Sunao Nakamura is one of the most experienced interventional cardiologist Japan. He had performed more than 25,000 cases of PCI and 10,000 cases of chronic total occlusion (CTO) which is a biggest numbers in the world. He has a very unique background as a researcher; studying about cellular electro-physiology for 6 years and clinical sciences for 4 years in his younger days. After that he suddenly changed his main field of cardiology; Interventional cardiology with respect of Prof. Shigeru Saito ; who was active in the leadership position in Asia region, Dr. Nakamura worked disseminate PCI in Asia from his age early 30s and experienced living a half of the year in foreign countries. As a result of through these actives over the years, he has built good relations with many doctors who share the same goals all over the world. His motto is that patients around the world should be saved not only we think about the patients who come here to our hospital by sharing each other’s skills and knowledge. He is also fully engaged in the leading edge of clinical activities and researches, and at his New Tokyo Hospital, many clinical and basic studies are conducted every year, and about 30 papers are published annually. Especially in close relation with Professor Antonio Colombo, Italy, our young doctors who received his guidance are active not only as a physician but also as a medical scientist in New Tokyo Hospital. His dream is to make the world's leading heart center capable of medical research from basic to clinical.