Live case demonstration: iFR Co-registration in anatomically tight but physiologically negative lesion

Dr Breda Hennessey graduated from the Third Faculty of Medicine in Charles University in Prague. Following this, she returned to Ireland to complete her general medical and higher specialist cardiology training. In 2019, she was awarded the Brian McGovern Scholarship by the Irish Cardiac Society, and this allowed her to commence her subspecialty training in Interventional Cardiology at Hospital Clínico San Carlos in Madrid. She completed a two-year coronary interventional fellowship, with a focus on intracoronary imaging, invasive physiology and ultra-low dose contrast intervention. Following completion of her coronary training, she undertook a further fellowship in structural intervention, also at Hospital Clínico San Carlos. In addition to her clinical work, she has been involved in various research projects pertaining to ultra-low dose contrast PCI, investigating the impact of new technologies in reducing contrast burden in complex PCI . She has authored and co-authored a number of research articles, book chapters and has contributed to the European association of Percutaneous Cardiovascular Interventions textbook. During her time at Hospital Clinico San Carlos, she completed a Masters in Interventional Cardiology and is currently undertaking a PHD at the Complutense University of Madrid with a focus in ultra-low dose contrast PCI. Throughout her fellowship, she regularly took part in the preparation and delivery of educational courses, both at Hospital Clinico San Carlos and in collaboration with other tertiary referral centres and international cardiology societies in Spain, the UK and the UAE.

Dr. Hernán Mejía-Rentería is an Interventional Cardiologist at the Department of Cardiology, Hospital Clinico San Carlos, Madrid, Spain. He graduated from the Medical School of Universidad del Valle (Colombia) and underwent specialty training in Cardiology at Hospital Clinico San Carlos, Madrid, Spain. Subsequently, he completed his subspecialty training as Interventional Cardiologist in 2017 at the same institution. Dr. Mejía-Rentería obtained a PhD (Cum Laude) in coronary physiology in 2021 at Universidad Complutense de Madrid. He is a member of European Association of Percutaneous Cardiovascular Interventions (EAPCI) and has published over 70 indexed scientific articles on coronary physiology, functional angiography, intracoronary imaging techniques and Takotsubo Syndrome, and is author of chapters in different academic textbooks. His main research areas at present include coronary physiology assessment with invasive and angiography derived techniques in patients with coronary artery disease or ischemia with non-obstructive coronary arteries.

Prof Javier Escaned is Head of Interventional Cardiology Section at Hospital Clinico San Carlos (Madrid, Spain). He trained as a cardiologist the United Kingdom before moving to the Thoraxcenter / Rotterdam (The Netherlands), where he obtained his PhD degree in 1994. With over 30 years of experience as interventionalist, he regularly serves as live case operator and educationalist in global events. He is author of over 500 PubMed indexed scientific articles (h-index 74) on topics that include complex PCI in multivessel disease, left main and chronic total occlusions. His track record in coronary physiology includes being investigator on pivotal FFR trials like DEFER (1998), collaborator with Justin Davies in the validation and clinical implementation of iFR (since 2010), and developer of new methods for the assessment of microvascular and non-obstructive coronary disease. Editorial work includes two large textbooks (“Coronary Stenosis. Imaging, Structure and Physiology” and “Physiological Assessment of Coronary Stenoses and the Microcirculation) and editorial board positions in scientific journals. Board positions in scientific societies include EuroPCR, EAPCI, EuroCTO and the ESC Working Group of Coronary Pathophysiology and Microcirculation. Additional interest incllude music and phylosophy. He is a recipient of the ESC Silver Medal and the 2022 ESC Andreas Gruentzig Award.

Niels van Royen is an interventional cardiologist and Head of Department of Cardiology at the Radboud University Medical Center, Nijmegen, the Netherlands. He has a background in pre-clinical research and is head of a research group on translational research in repair mechanisms in ischemic heart disease. Also he is principal investigator of several multi-center clinical trials like the TRANSIENT, COACT, REDUCE-MVI and iMODERN. These trials focus on timing of interventional procedures as well as the use of intra-coronary physiology to guide interventional procedures both in stable coronary artery disease as well as acute coronary syndromes.