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- Instantaneous wave-Free Ratio (iFR)
- Fractional Flow Reserve (FFR)
- Coronary Flow Reserve (CFR)
- Coronary Physiology
Terminology and Descriptions of the Index Abbreviations - Dr. Ricardo Petraco
Summary
Speaker: Dr Ricardo Petraco, Imperial College Healthcare NHS Trust, London
Ricardo Petraco discusses different physiological indices, and explains the derivation and methods for calculation...
Summary
Speaker: Dr Ricardo Petraco, Imperial College Healthcare NHS Trust, London
Ricardo Petraco discusses different physiological indices, and explains the derivation and methods for calculation of each index.
Key learning points:
- 1. Pd/Pa, FFR (Fractional Flow Reserve) , and iFR (Instantaneous Wave-free ration) are pressure-only indices measures using a ratio of the Pd (wire pressure) and Pa (aortic pressure)
- 2. Pd/Pa and FFR are measured across the entire cardiac cycle, typically using a moving average of 3-5 beats
- 3. iFR is measured over a phase in diastole, the Wave Free-period where resistance is low and most stable
- 4. CFR (Coronary Flow Reserve) is the ratio of mean basal flow by mean hyperaemic flow
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Speakers
Ricardo Petraco
Speaker
Dr Ricardo Petraco is a NIHR Lecturer in interventional Cardiology at Imperial College London,... Dr Ricardo Petraco is a NIHR Lecturer in interventional Cardiology at Imperial College London, performing his clinical work at Hammersmith Hospital. He has been working with coronary physiology at Imperial since 2010 on the development of the novel instantaneous wave-Free Ratio (iFR). Dr Petraco’s work with iFR has led to the proposition of the Hybrid iFR-FFR approach and has established iFR’s close relationship with coronary flow reserve (CFR). His interests in computer programming has led to the development of a software for automated analysis of coronary haemodynamics signals which is been used by many leading centres in the world. He has also pioneered the algorithm for iFR calculation without the need for an ECG signal, an approach which is now implemented in clinical consoles. He has secured several research grants and published extensively in the field of coronary physiology. His current research interests are on the development of methodologies to assess stenosis severity in situations of haemodynamic instability and on the understanding of how medical therapies modulate coronary resistance and flow. Clinically, his interests also include the use of intravascular imaging modalities to optimise PCI and has been engaged in IVUS training for cathlab staff and cardiology trainees.
