Planning and guidance of complex percutaneous coronary interventions

Prof Javier Escaned is Head of Section (Interventional Cardiology Section) at Hospital Clinico San Carlos / Complutense University (Madrid, Spain). He trained in the United Kingdom as Specialist in Cardiology and obtained his PhD in The Netherlands. Author of >600 indexed scientific articles on interventional cardiology, imaging and physiology (h-index 74) and over 30 years of experience as PCI operator, he regularly lectures and performs live cases at major scientific and educational meetings. He is a recipient of the European Society of Cardiology (ESC) Silver Medal and the Andreas Grüntzig Award for his contributions to the fiedl fo Interventional Cardiology. Main areas of expertise include complex PCI, intracoronary diagnostics and functional coronary angiography. His track record in coronary physiology comprises being investigator on pioneer FFR trials like DEFER (1998), collaborator with Justin Davies in the validation and clinical implementation of iFR, and developer of new tools for the assessment of coronary microcirculation. Editorial roles include Deputy Editor EHJ, Advisory Editor Eurointervention, editor of the textbooks “Coronary Stenosis: Imaging, Structure and Physiology” and “Physiological Assessment of Coronary Stenoses and the Microcirculation". Recent board positions include EAPCI board / Education Committee Chair, ESC WG Coronary Pathophysiology and Microcirculation, EuroCTO Board. Recent trials as Principal Investigator include ADVISE II, DEFINE FLAIR, SYNTAX II, PIONEER IV, Cerebral-Coronary-Connection (C3), DCR4Contrast, INOCA LongCovid and AID ANGIO. Additional interests are philosophy and music.

Dr Justin Davies is a honorary 
interventional cardiologist at Hammersmith Hospital, Imperial College NHS Trust, London. After training at Imperial College, he won a prestigious BHF research fellowship to study arterial haemodynamics. Since then he has continued to
work on the development of mathematical algorithms to aid understanding of large artery physiology and to develop new tools to assess arterial disease. The holder of several patents,
he has published widely in the field of hypertension, coronary and large artery physiology and is the winner of many national and international awards. He has several international collaborations, and is the developer of iFR and the co-principal investigator of the ADVISE studies, the DEFINE-FLAIR, ORBITA and DEFINE-PCI studies. Justin also has an interest in renal denervation, and has lead the first-in-man studies to evaluate the safety of this technique to patients with chronic systolic heart failure (REACH studies).

Tommaso Gori is Professor for translational vascular medicine at the University Medical Center of Mainz, Germany where he also leads the Cardiac Catheterization Laboratory and the Clinical Study Center. He obtained his title of Dottore in Medicina e Chirurgia (MD equivalent) from the University of Siena, Italy, and his PhD from the University of Toronto, Canada. He has worked in Siena, Italy, Toronto, Canada and Mainz, Germany. Dr Gori was winner of 19 international awards, among which the American Heart Association – S.A. Levine Young Investigator Award and the Young Investigator Award of the American College of Cardiology, both in the year 2001. Dr Gori has authored 300 peer-reviewed papers in the fields of endothelial (dys)function, mechanisms of action and effects of organic nitrates, physiology of the coronary circulation, oxidative stress, ischemic preconditioning, microcirculation and hemorheology and interventional cardiology (h-index 38). Dr Gori´s areas of clinical expertise include structural, peripheral and coronary interventions and imaging modalities.

Prof Javier Escaned is Head of Section (Interventional Cardiology Section) at Hospital Clinico San Carlos / Complutense University (Madrid, Spain). He trained in the United Kingdom as Specialist in Cardiology and obtained his PhD in The Netherlands. Author of >600 indexed scientific articles on interventional cardiology, imaging and physiology (h-index 74) and over 30 years of experience as PCI operator, he regularly lectures and performs live cases at major scientific and educational meetings. He is a recipient of the European Society of Cardiology (ESC) Silver Medal and the Andreas Grüntzig Award for his contributions to the fiedl fo Interventional Cardiology. Main areas of expertise include complex PCI, intracoronary diagnostics and functional coronary angiography. His track record in coronary physiology comprises being investigator on pioneer FFR trials like DEFER (1998), collaborator with Justin Davies in the validation and clinical implementation of iFR, and developer of new tools for the assessment of coronary microcirculation. Editorial roles include Deputy Editor EHJ, Advisory Editor Eurointervention, editor of the textbooks “Coronary Stenosis: Imaging, Structure and Physiology” and “Physiological Assessment of Coronary Stenoses and the Microcirculation". Recent board positions include EAPCI board / Education Committee Chair, ESC WG Coronary Pathophysiology and Microcirculation, EuroCTO Board. Recent trials as Principal Investigator include ADVISE II, DEFINE FLAIR, SYNTAX II, PIONEER IV, Cerebral-Coronary-Connection (C3), DCR4Contrast, INOCA LongCovid and AID ANGIO. Additional interests are philosophy and music.

Dr Kambis Mashayekhi is Head of the Department of Internal Medicine and Cardiology in Heart Center Lahr in Germany. Dr. Mashayekhi is performing over 350 CTO-PCI’s per year and is an world-renowned CTO and complex PCI specialist. Dr. Mashayekhi is the head of the CTO working group from the German Society of cardiology and the Co-Director of MLCTO and EuroCTO course. He is the new EuroCTO president elect for 2023.

Dr Alfonso Jurado-Román is currently Interventional cardiologist at La Paz University Hospital (Madrid). He was graduated in Medicine from the Complutense University of Madrid (Extraordinary Award and Scholarship for academic excellence from the Community of Madrid) and did his training in Cardiology and Interventional Cardiology at University Hospital 12 de Octubre (Madrid). He achieved his PhD degree in Myocardial Infarction at 2015 from the Complutense University of Madrid. He has developed great interest in cardiomyopathies, with training at the Heart Hospital in London and working as research collaborator at University Hospital 12 de Octubre. He has been professor of Cardiology during seven years and professor of statistics during 2 years. He has been the Cardiology Trainee Program Tutor while his period at the University General Hospital of Ciudad Real. He is author of 85 Scientific publications in international journals and 185 book chapters. Currently his main interest in interventional cardiology are Complex PCI, including chronic total occlusions and calcified lesions, and intracoronary imaging and Physiology. He is currently coordinating these areas at University Hospital La Paz and is the principal investigator of several studies in this field as Roller Coaster Trial (Rotational Atherectomy, Lithotripsy or laser in calcified lesions) and LUDICO study (Coronary laser at undilatable and uncrossable lesions). He is member of EuroCTO club an also of Euro4C. In addition, he is member of the European Association of Percutaneous coronary interventions (EAPCI), member of the ESC working group on Myocardial and pericardial diseases and member of the ESC working group on Acute cardiac care. He has also coursed a Master in Clinical Management, Medical and Assistance Management and a Master in Current Approach to Structural Heart Disease.

Angela McInerney is an Interventional Cardiologist at University Hospital Galway, Ireland. Following completion of her basic cardiology training in Ireland she was awarded the Brian McGovern Travelling Fellowship grant from the Irish Board for Cardiology Training in 2018 which allowed her to start her interventional fellowship in Hospital Clínico San Carlos, Madrid, Spain. Following two years of coronary training including complex PCI, she was awarded an European Society of Cardiology Fellowship Training Grant and completed a further year of structural intervention also in Clínico San Carlos, Madrid. Her specialist interests are in intracoronary imaging, intracoronary physiology, calcium modification techniques and complex PCI. She has been keenly involved in various research projects pertaining to intracoronary physiology and intravascular imaging having authored and co-authored a number of research articles as well as review articles and book chapters on these topics. During her fellowship she also regularly partook in the preparation and delivery of educational courses in Clínico San Carlos and values the educational aspect of her role as a Consultant Interventional Cardiologist.

Dr Ashok Seth is Chairman of Fortis Escorts Heart Institute, New Delhi and Adjunct Professor of Cardiology at JN Medical College (Aligarh Muslim University) and National Board of Examinations. Dr Seth has led the field of Interventional Cardiology for last 33-years and has contributed extensively to the development, scientific progress and education in this field and pioneered numerous angioplasty techniques for India and Asia Pacific. Dr Seth has been awarded by the National Honour of Padma Shri in 2003, Padma Bhushan in 2015 and ‘B.C.Roy National Award’ for the ‘Eminent Medical Person’ by the President of India in 2017. He has also been awarded the National Honour of Republic of Spain “Crus Officer with Insignia Order of Isabella the Catholic”, Master Interventionalist (MSCAI) by the Society for Cardiovascular Angiography & Interventions (USA) in addition to 90 other national and international awards. Dr Seth has been honoured by Doctorates from six prestigious national universities. He has been conferred ‘Adjunct Professorship of Cardiology’ of J N Medical College, Aligarh Muslim University and the National Board of Examinations. He is Founder/Course Director of five major National & International Teaching Courses - India Live, India Valves, CHIP-CTO India, AICT-AsiaPCR and Imaging & Physiology Council of India. He is also Associate Director of TCT Scientific Sessions (USA) and Program Committee Member of EuroPCR. Dr Seth has been invited to lecture at more than 600 national & international meetings and to teach complex angioplasty techniques through Live Demonstration at more than 150 national & international meetings around the world. He has more than 400-publications to his credit in peer reviewed Indian and International medical journals and has chapters in 30-books on Cardiology and has been the Editor of 3-books. He is an acclaimed teacher and has trained more than 500-cardiologists of India and abroad in advanced techniques of angioplasty.

Dr Justin Davies is a honorary 
interventional cardiologist at Hammersmith Hospital, Imperial College NHS Trust, London. After training at Imperial College, he won a prestigious BHF research fellowship to study arterial haemodynamics. Since then he has continued to
work on the development of mathematical algorithms to aid understanding of large artery physiology and to develop new tools to assess arterial disease. The holder of several patents,
he has published widely in the field of hypertension, coronary and large artery physiology and is the winner of many national and international awards. He has several international collaborations, and is the developer of iFR and the co-principal investigator of the ADVISE studies, the DEFINE-FLAIR, ORBITA and DEFINE-PCI studies. Justin also has an interest in renal denervation, and has lead the first-in-man studies to evaluate the safety of this technique to patients with chronic systolic heart failure (REACH studies).

Dr Nieves Gonzalo is Consultant Interventional Cardiologist at the Interventional Cardiology Department at Clinico San Carlos University Hospital in Madrid. She obtained her Specialist Certification in Cardiology after training at Clinico San Carlos University Hospital in Madrid. Subsequently, she underwent a research fellowship at Thoraxcenter, Erasmus University Rotterdam (The Netherlands) under the supervision of Professor Patrick Serruys, focused mainly in intracoronary imaging and bioabsorbable stents. In 2010 she obtained her PhD with the thesis “Optical coherence tomography for the assessment of coronary atherosclerosis and vessel response after stent implantation”. Her track record includes over 170 articles indexed in PubMed, as well as book chapters in Interventional Cardiology textbooks. Recent research projects as principal investigator includes a study about the assessment of neoatherosclerosis and its clinical impact in patients with restenosis (RIBS IV and V OCT substudy) and research regarding vessel injury and healing evaluation with different stent platforms evaluated with OCT (VISTA study). Dr Gonzalo is a dedicated educationalist with involvement in many areas of complex PCI, serving currently as Deputy Editor for Eurointervention and Committee Member of EuroPCR.

Dr Dejan Milasinovic is an interventional cardiologist at the Department of Cardiology, Clinical Center of Serbia. He is also an Assistant Professor at Faculty of Medicine, University of Belgrade. His main research interests focus in the fields of the invasive treatment of acute coronary syndromes and complex coronary interventions, with an emphasis on bifurcation PCI and intracoronary guidance. In 2016, Dr Milasinovic received the EuroPCR 2016 Best Abstract award, for a work on the timing of invasive coronary intervention in patients with non-ST-segment elevation myocardial infarction. He is a member of European Association of Percutaneous Cardiovascular Interventions (EAPCI) and has served as program committee member of the annual EuroPCR conference. Dr Milasinovic also serves on the editorial boards of EuroIntervention (editorial consultant) and PCRonline and is the Chair of the EAPCI Young committee.

Prof Javier Escaned is Head of Section (Interventional Cardiology Section) at Hospital Clinico San Carlos / Complutense University (Madrid, Spain). He trained in the United Kingdom as Specialist in Cardiology and obtained his PhD in The Netherlands. Author of >600 indexed scientific articles on interventional cardiology, imaging and physiology (h-index 74) and over 30 years of experience as PCI operator, he regularly lectures and performs live cases at major scientific and educational meetings. He is a recipient of the European Society of Cardiology (ESC) Silver Medal and the Andreas Grüntzig Award for his contributions to the fiedl fo Interventional Cardiology. Main areas of expertise include complex PCI, intracoronary diagnostics and functional coronary angiography. His track record in coronary physiology comprises being investigator on pioneer FFR trials like DEFER (1998), collaborator with Justin Davies in the validation and clinical implementation of iFR, and developer of new tools for the assessment of coronary microcirculation. Editorial roles include Deputy Editor EHJ, Advisory Editor Eurointervention, editor of the textbooks “Coronary Stenosis: Imaging, Structure and Physiology” and “Physiological Assessment of Coronary Stenoses and the Microcirculation". Recent board positions include EAPCI board / Education Committee Chair, ESC WG Coronary Pathophysiology and Microcirculation, EuroCTO Board. Recent trials as Principal Investigator include ADVISE II, DEFINE FLAIR, SYNTAX II, PIONEER IV, Cerebral-Coronary-Connection (C3), DCR4Contrast, INOCA LongCovid and AID ANGIO. Additional interests are philosophy and music.

Dr Justin Davies is a honorary 
interventional cardiologist at Hammersmith Hospital, Imperial College NHS Trust, London. After training at Imperial College, he won a prestigious BHF research fellowship to study arterial haemodynamics. Since then he has continued to
work on the development of mathematical algorithms to aid understanding of large artery physiology and to develop new tools to assess arterial disease. The holder of several patents,
he has published widely in the field of hypertension, coronary and large artery physiology and is the winner of many national and international awards. He has several international collaborations, and is the developer of iFR and the co-principal investigator of the ADVISE studies, the DEFINE-FLAIR, ORBITA and DEFINE-PCI studies. Justin also has an interest in renal denervation, and has lead the first-in-man studies to evaluate the safety of this technique to patients with chronic systolic heart failure (REACH studies).

Dr. Pablo Salinas is Interventional Cardiologist at Hospital Clínico San Carlos in Madrid, Spain. He studied Medicine at Universidad Complutense in Madrid, Spain and was trained in Cardiology and Interventional Cardiology at Hospital La Paz in Madrid, Spain. In 2015 he obtained his PhD degree (cum laude) at the Universidad Autonoma in Madrid. He has developed his professional career in the field of interventional cardiology for over 10 years, and is a skilled operator in complex coronary intervention, chronic occlusions, and stroke prevention therapies such as foramen ovale closure and appendage closure, with regular participation in educational events and live cases. During his research career he has 80+ PubMed indexed publications and is currently the PI of three multicenter studies SUGAR Trial (NCT03321032), REVASEC Registry (NCT03349385), and TROMPA Registry. Also he has been researcher in several investigator initiated, competitive funding research (PI16 / 00840, PIE16 / 00043, PI15 / 00742).

Dr Breda Hennessey graduated from the Third Faculty of Medicine in Charles University in Prague. Following this, she returned to Ireland to complete her general medical and higher specialist cardiology training. In 2019, she was awarded the Brian McGovern Scholarship by the Irish Cardiac Society, and this allowed her to commence her subspecialty training in Interventional Cardiology at Hospital Clínico San Carlos in Madrid. She completed a two-year coronary interventional fellowship, with a focus on intracoronary imaging, invasive physiology and ultra-low dose contrast intervention. Following completion of her coronary training, she undertook a further fellowship in structural intervention, also at Hospital Clínico San Carlos. In addition to her clinical work, she has been involved in various research projects pertaining to ultra-low dose contrast PCI, investigating the impact of new technologies in reducing contrast burden in complex PCI . She has authored and co-authored a number of research articles, book chapters and has contributed to the European association of Percutaneous Cardiovascular Interventions textbook. During her time at Hospital Clinico San Carlos, she completed a Masters in Interventional Cardiology and is currently undertaking a PHD at the Complutense University of Madrid with a focus in ultra-low dose contrast PCI. Throughout her fellowship, she regularly took part in the preparation and delivery of educational courses, both at Hospital Clinico San Carlos and in collaboration with other tertiary referral centres and international cardiology societies in Spain, the UK and the UAE.

Prof Javier Escaned is Head of Section (Interventional Cardiology Section) at Hospital Clinico San Carlos / Complutense University (Madrid, Spain). He trained in the United Kingdom as Specialist in Cardiology and obtained his PhD in The Netherlands. Author of >600 indexed scientific articles on interventional cardiology, imaging and physiology (h-index 74) and over 30 years of experience as PCI operator, he regularly lectures and performs live cases at major scientific and educational meetings. He is a recipient of the European Society of Cardiology (ESC) Silver Medal and the Andreas Grüntzig Award for his contributions to the fiedl fo Interventional Cardiology. Main areas of expertise include complex PCI, intracoronary diagnostics and functional coronary angiography. His track record in coronary physiology comprises being investigator on pioneer FFR trials like DEFER (1998), collaborator with Justin Davies in the validation and clinical implementation of iFR, and developer of new tools for the assessment of coronary microcirculation. Editorial roles include Deputy Editor EHJ, Advisory Editor Eurointervention, editor of the textbooks “Coronary Stenosis: Imaging, Structure and Physiology” and “Physiological Assessment of Coronary Stenoses and the Microcirculation". Recent board positions include EAPCI board / Education Committee Chair, ESC WG Coronary Pathophysiology and Microcirculation, EuroCTO Board. Recent trials as Principal Investigator include ADVISE II, DEFINE FLAIR, SYNTAX II, PIONEER IV, Cerebral-Coronary-Connection (C3), DCR4Contrast, INOCA LongCovid and AID ANGIO. Additional interests are philosophy and music.

Dr Justin Davies is a honorary 
interventional cardiologist at Hammersmith Hospital, Imperial College NHS Trust, London. After training at Imperial College, he won a prestigious BHF research fellowship to study arterial haemodynamics. Since then he has continued to
work on the development of mathematical algorithms to aid understanding of large artery physiology and to develop new tools to assess arterial disease. The holder of several patents,
he has published widely in the field of hypertension, coronary and large artery physiology and is the winner of many national and international awards. He has several international collaborations, and is the developer of iFR and the co-principal investigator of the ADVISE studies, the DEFINE-FLAIR, ORBITA and DEFINE-PCI studies. Justin also has an interest in renal denervation, and has lead the first-in-man studies to evaluate the safety of this technique to patients with chronic systolic heart failure (REACH studies).

Dr Miroslaw Ferenc is a Director of Interventional Cardiology Department, Cardiology and Angiology II at University Heartcenter Freiburg in Bad Krozingen

Dr. Pinilla-Echeverri is originally from Colombia and received her MD from Universidad de Caldas in Manizales, Caldas, Colombia. She moved to Spain to complete training in Internal Medicine and Cardiology and then moved to Canada to complete an Interventional Cardiology, non-invasive Cardiac Computed Tomography Angiography imaging and advanced Intracoronary Imaging fellowship at McMaster University, Hamilton, Canada. She also obtained a Master’s Degree in Health Research Methodology from Universidad de Cordoba; and PhD Degree from Universidad Complutense in Madrid, Spain. She actively participates in Acute Coronary Syndrome research at the Population Health Research Institute. Dr. Pinilla-Echeverri is an Associate Professor at the Department of Medicine Division of Cardiology at McMaster University and currently an Interventional Cardiology Staff at Hamilton Health Sciences and Niagara Health. She is the Program Director of the Intravascular Coronary Imaging Fellowship in McMaster University and has trained international interventional cardiologists in Imaging. She is passionate about acute coronary syndrome research and leads educational programs worldwide.

Dr Nieves Gonzalo is Consultant Interventional Cardiologist at the Interventional Cardiology Department at Clinico San Carlos University Hospital in Madrid. She obtained her Specialist Certification in Cardiology after training at Clinico San Carlos University Hospital in Madrid. Subsequently, she underwent a research fellowship at Thoraxcenter, Erasmus University Rotterdam (The Netherlands) under the supervision of Professor Patrick Serruys, focused mainly in intracoronary imaging and bioabsorbable stents. In 2010 she obtained her PhD with the thesis “Optical coherence tomography for the assessment of coronary atherosclerosis and vessel response after stent implantation”. Her track record includes over 170 articles indexed in PubMed, as well as book chapters in Interventional Cardiology textbooks. Recent research projects as principal investigator includes a study about the assessment of neoatherosclerosis and its clinical impact in patients with restenosis (RIBS IV and V OCT substudy) and research regarding vessel injury and healing evaluation with different stent platforms evaluated with OCT (VISTA study). Dr Gonzalo is a dedicated educationalist with involvement in many areas of complex PCI, serving currently as Deputy Editor for Eurointervention and Committee Member of EuroPCR.

Dr Richard A. Shlofmitz, MD, FACC is the Chairman of Cardiology at St. Francis Hospital, The Heart Center®, in Roslyn, New York. A pioneer in interventional cardiology, Dr. Shlofmitz has worked to advance the field, with a focus on optimizing outcomes with the development of Precision PCI. He is a founding co-director of the annual Intravascular Imaging and Coronary Physiology Workshop. Performing over 1,000 coronary interventions annually, he has one of the largest volumes of experience in PCI. He has the most clinical experience with orbital atherectomy and OCT world-wide. His clinical research interests focus on optimizing coronary interventions and he serves on multiple scientific advisory boards and clinical trial steering committees to further this mission. Dr Shlofmitz has been one of the largest enrollers for multiple clinical trials, including TWILIGHT, ILUMIEN III, and Onyx, with more than 75 publications in peer-reviewed journals and was first to perform coronary intravascular lithotripsy (IVL) in North America as part of the DISRUPT CAD III trial.

Prof Amir Lerman Is an endowed named Barbara Lips professor of medicine and a consultant in the department of cardiovascular disease at the Mayo graduate school of medicine. Prof. Lerman graduated from the Technion school of Medicine in Haifa Israel and completed his training in internal medicine, cardiovascular diseases and invasive cardiology at the Mayo Clinic Prof. Lerman serves as an associate chair of the department of Cardiovascular medicine and the Director of the Mayo Clinic cardiovascular research center, the medical director of the chest pain and coronary physiology clinic. Prof. Lerman’s interest is the coronary physiology and imaging and the role of novel therapy of the microcirculation and endothelial function in cardiovascular diseases. Prof. Lerman’s research program is also active and publishes in the area regenerative medicine, innovative technologies and digital health. Prof. Lerman published more than 800 manuscripts, book chapters and reviews; the NIH, AHA, and several foundations support his research.

Dr Dejan Milasinovic is an interventional cardiologist at the Department of Cardiology, Clinical Center of Serbia. He is also an Assistant Professor at Faculty of Medicine, University of Belgrade. His main research interests focus in the fields of the invasive treatment of acute coronary syndromes and complex coronary interventions, with an emphasis on bifurcation PCI and intracoronary guidance. In 2016, Dr Milasinovic received the EuroPCR 2016 Best Abstract award, for a work on the timing of invasive coronary intervention in patients with non-ST-segment elevation myocardial infarction. He is a member of European Association of Percutaneous Cardiovascular Interventions (EAPCI) and has served as program committee member of the annual EuroPCR conference. Dr Milasinovic also serves on the editorial boards of EuroIntervention (editorial consultant) and PCRonline and is the Chair of the EAPCI Young committee.

Dr. Hernán Mejía-Rentería is an Interventional Cardiologist at the Department of Cardiology, Hospital Clinico San Carlos, Madrid, Spain. He graduated from the Medical School of Universidad del Valle (Colombia) and underwent specialty training in Cardiology at Hospital Clinico San Carlos, Madrid, Spain. Subsequently, he completed his subspecialty training as Interventional Cardiologist in 2017 at the same institution. Dr. Mejía-Rentería obtained a PhD (Cum Laude) in coronary physiology in 2021 at Universidad Complutense de Madrid. He is a member of European Association of Percutaneous Cardiovascular Interventions (EAPCI) and has published over 70 indexed scientific articles on coronary physiology, functional angiography, intracoronary imaging techniques and Takotsubo Syndrome, and is author of chapters in different academic textbooks. His main research areas at present include coronary physiology assessment with invasive and angiography derived techniques in patients with coronary artery disease or ischemia with non-obstructive coronary arteries.

Prof Javier Escaned is Head of Section (Interventional Cardiology Section) at Hospital Clinico San Carlos / Complutense University (Madrid, Spain). He trained in the United Kingdom as Specialist in Cardiology and obtained his PhD in The Netherlands. Author of >600 indexed scientific articles on interventional cardiology, imaging and physiology (h-index 74) and over 30 years of experience as PCI operator, he regularly lectures and performs live cases at major scientific and educational meetings. He is a recipient of the European Society of Cardiology (ESC) Silver Medal and the Andreas Grüntzig Award for his contributions to the fiedl fo Interventional Cardiology. Main areas of expertise include complex PCI, intracoronary diagnostics and functional coronary angiography. His track record in coronary physiology comprises being investigator on pioneer FFR trials like DEFER (1998), collaborator with Justin Davies in the validation and clinical implementation of iFR, and developer of new tools for the assessment of coronary microcirculation. Editorial roles include Deputy Editor EHJ, Advisory Editor Eurointervention, editor of the textbooks “Coronary Stenosis: Imaging, Structure and Physiology” and “Physiological Assessment of Coronary Stenoses and the Microcirculation". Recent board positions include EAPCI board / Education Committee Chair, ESC WG Coronary Pathophysiology and Microcirculation, EuroCTO Board. Recent trials as Principal Investigator include ADVISE II, DEFINE FLAIR, SYNTAX II, PIONEER IV, Cerebral-Coronary-Connection (C3), DCR4Contrast, INOCA LongCovid and AID ANGIO. Additional interests are philosophy and music.

Tim van de Hoef, MD, PhD, FESC, is an interventional cardiology fellow at the Amsterdam UMC - VU Medical Center (Amsterdam, The Netherlands). He has been involved in intracoronary physiology research since 2010, and his research has covered the wide spectrum of intracoronary physiology assessed by means of invasive coronary pressure and flow measurements, ranging from functional stenosis severity appraisal to assessment of microvascular function in both stable coronary artery disease and acute coronary syndromes. He obtained a PhD (Cum Laude) in invasive coronary physiology in 2015. He has (co-)authored over 90 papers on the topic of coronary physiology, and his recent research has focused on the use of basal conditions for the assessment of epicardial stenosis severity, and the combined assessment of epicardial and microvascular disease to optimize diagnosis and risk-stratification in ischemic heart disease.

Prof Javier Escaned is Head of Section (Interventional Cardiology Section) at Hospital Clinico San Carlos / Complutense University (Madrid, Spain). He trained in the United Kingdom as Specialist in Cardiology and obtained his PhD in The Netherlands. Author of >600 indexed scientific articles on interventional cardiology, imaging and physiology (h-index 74) and over 30 years of experience as PCI operator, he regularly lectures and performs live cases at major scientific and educational meetings. He is a recipient of the European Society of Cardiology (ESC) Silver Medal and the Andreas Grüntzig Award for his contributions to the fiedl fo Interventional Cardiology. Main areas of expertise include complex PCI, intracoronary diagnostics and functional coronary angiography. His track record in coronary physiology comprises being investigator on pioneer FFR trials like DEFER (1998), collaborator with Justin Davies in the validation and clinical implementation of iFR, and developer of new tools for the assessment of coronary microcirculation. Editorial roles include Deputy Editor EHJ, Advisory Editor Eurointervention, editor of the textbooks “Coronary Stenosis: Imaging, Structure and Physiology” and “Physiological Assessment of Coronary Stenoses and the Microcirculation". Recent board positions include EAPCI board / Education Committee Chair, ESC WG Coronary Pathophysiology and Microcirculation, EuroCTO Board. Recent trials as Principal Investigator include ADVISE II, DEFINE FLAIR, SYNTAX II, PIONEER IV, Cerebral-Coronary-Connection (C3), DCR4Contrast, INOCA LongCovid and AID ANGIO. Additional interests are philosophy and music.

Dr Justin Davies is a honorary 
interventional cardiologist at Hammersmith Hospital, Imperial College NHS Trust, London. After training at Imperial College, he won a prestigious BHF research fellowship to study arterial haemodynamics. Since then he has continued to
work on the development of mathematical algorithms to aid understanding of large artery physiology and to develop new tools to assess arterial disease. The holder of several patents,
he has published widely in the field of hypertension, coronary and large artery physiology and is the winner of many national and international awards. He has several international collaborations, and is the developer of iFR and the co-principal investigator of the ADVISE studies, the DEFINE-FLAIR, ORBITA and DEFINE-PCI studies. Justin also has an interest in renal denervation, and has lead the first-in-man studies to evaluate the safety of this technique to patients with chronic systolic heart failure (REACH studies).