An Introduction to iFR: Concepts, Principals, and Limitations - Dr. Justin Davies
Summary
Dr Justin Davies, Consultant Cardiologist, Imperial College London, UK
Dr Justin Davies introduces iFR (Instantaneous Wave-free Ratio), and discuses the concepts, principals and limitations....
Summary
Dr Justin Davies, Consultant Cardiologist, Imperial College London, UK
Dr Justin Davies introduces iFR (Instantaneous Wave-free Ratio), and discuses the concepts, principals and limitations.
Key learning points:-
- 1. Diastole provides the most sensitive phase of the cardiac cycle to identify stenosis severity
- 2. Pressure is proportional to flow when resistance is stable
- 3. In FFR resistance is stabilised using powerful vasodilator such as adenosine
- 4. In iFR resistance is stabilised by analysing the cardiac cycle over the diastolic Wave-free Period, without the need for drug administration
- 5. Pharmacological hyperaemia differs markedly from exercise induced hyperaemia
- 6. iFR provides a direct measure of the vasodilatory effect on the coronary microcirculation
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